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Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects / Sintomas neuropsiquiátricos na demência vascular: aspectos clínicos e epidemiológicos
Santos, Marcelo Antônio Oliveira; Bezerra, Lucas Soares; Correia, Carolina da Cunha; Bruscky, Igor Silvestre.
  • Santos, Marcelo Antônio Oliveira; Federal University of Pernambuco. Epidemiology and Cardiology Research Group. Recife. BR
  • Bezerra, Lucas Soares; Federal University of Pernambuco. Epidemiology and Cardiology Research Group. Recife. BR
  • Correia, Carolina da Cunha; Federal University of Pernambuco. Epidemiology and Cardiology Research Group. Recife. BR
  • Bruscky, Igor Silvestre; Federal University of Pernambuco. Epidemiology and Cardiology Research Group. Recife. BR
Dement. neuropsychol ; 12(1): 40-44, Jan.-Mar. 2018. tab, graf
Article in English | LILACS | ID: biblio-891051
ABSTRACT
ABSTRACT Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases.

Objective:

To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia.

Methods:

A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS).

Results:

81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI 1.36-27.9, p = 0.02).

Conclusion:

Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS.
RESUMO
RESUMO Demência é uma terminologia geral para um grupo heterogêneo de doenças orgânicas e neurodegenerativas. As causas cerebrovasculares são responsáveis por 20% dos casos.

Objetivo:

Descrever as características clínicas e epidemiológicas de indivíduos maiores de 60 anos diagnosticados com demência vascular ou mista em hospital de referência em demência.

Métodos:

Estudo retrospectivo descritivo de 2014 a 2017 em idosos com demência. Outras formas de demência ou uso de medicamentos que mimetizem distúrbios cognitivos foram excluídos. O inventário neuropsiquiátrico de 12 itens foi usado para avaliar os sintomas neuropsiquiátricos (SNP).

Resultados:

81.1% dos pacientes apresentaram SNP, apenas 15% tiveram dois ou mais. Apatia foi o mais frequente (56,6%). Houve associação entre CDR 1 ou 2 e SNP (OR = 6.16, 95% CI 1.36-27.9, p = 0.02).

Conclusão:

Geralmente há um sintoma isolado, sendo apatia o principal. Encontramos associação entre demência leve e moderada e SNP.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Behavioral Symptoms / Aged / Dementia, Vascular / Neurologic Manifestations Type of study: Diagnostic study / Observational study / Risk factors Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Pernambuco/BR

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Full text: Available Index: LILACS (Americas) Main subject: Behavioral Symptoms / Aged / Dementia, Vascular / Neurologic Manifestations Type of study: Diagnostic study / Observational study / Risk factors Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Pernambuco/BR