Your browser doesn't support javascript.
loading
Partial nephrectomy for T3aN0M0 renal cell carcinoma: shall we step forward?
Peng, Ding; He, Zhi-song; Li, Xue-song; Tang, Qi; Zhang, Lei; Yang, Kai-wei; Yu, Xiao-teng; Zhang, Cui-jian; Zhou, Li-qun.
  • Peng, Ding; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • He, Zhi-song; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Li, Xue-song; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Tang, Qi; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Zhang, Lei; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Yang, Kai-wei; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Yu, Xiao-teng; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Zhang, Cui-jian; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
  • Zhou, Li-qun; Peking University First Hospital. Institute of Urology. Department of Urology. Beijing. CN
Int. braz. j. urol ; 43(5): 849-856, Sept.-Oct. 2017. tab, graf
Article in English | LILACS | ID: biblio-892898
ABSTRACT
ABSTRACT

Objectives:

To evaluate the prognosis of non-metastatic T3a renal cell carcinoma (RCC) with partial nephrectomy (PN). Patients and

Methods:

We retrospectively evaluated 125 patients with non-metastatic T3a RCC. Patients undergoing PN and radical nephrectomy (RN) were strictly matched by clinic-pathologic characteristics. Log-rank test and Cox regression model were used for univariate and multivariate analysis.

Results:

18 pair patients were matched and the median follow-up was 35.5 (10-86) months. PN patients had a higher postoperative eGFR than RN patients (P=0.034). Cancer-specific survival (CSS) and recurrence-free survival (RFS) did not differ between two groups (P=0.305 and P=0.524). On multivariate analysis, CSS decreased with positive surgical margin and anemia (both P <0.01) and RFS decreased with Furhman grade, positive surgical margin, and anemia (all P<0.01).

Conclusions:

For patients with non-metastatic pT3a RCC, PN may be a possible option for similar oncology outcomes and better renal function.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Renal Cell / Kidney Neoplasms / Nephrectomy Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2017 Type: Article Affiliation country: China Institution/Affiliation country: Peking University First Hospital/CN

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Renal Cell / Kidney Neoplasms / Nephrectomy Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2017 Type: Article Affiliation country: China Institution/Affiliation country: Peking University First Hospital/CN