Partial nephrectomy for T3aN0M0 renal cell carcinoma: shall we step forward?
Int. braz. j. urol
;
43(5): 849-856, Sept.-Oct. 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-892898
ABSTRACT
ABSTRACT Objectives:
To evaluate the prognosis of non-metastatic T3a renal cell carcinoma (RCC) with partial nephrectomy (PN). Patients andMethods:
We retrospectively evaluated 125 patients with non-metastatic T3a RCC. Patients undergoing PN and radical nephrectomy (RN) were strictly matched by clinic-pathologic characteristics. Log-rank test and Cox regression model were used for univariate and multivariate analysis.Results:
18 pair patients were matched and the median follow-up was 35.5 (10-86) months. PN patients had a higher postoperative eGFR than RN patients (P=0.034). Cancer-specific survival (CSS) and recurrence-free survival (RFS) did not differ between two groups (P=0.305 and P=0.524). On multivariate analysis, CSS decreased with positive surgical margin and anemia (both P <0.01) and RFS decreased with Furhman grade, positive surgical margin, and anemia (all P<0.01).Conclusions:
For patients with non-metastatic pT3a RCC, PN may be a possible option for similar oncology outcomes and better renal function.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Carcinoma, Renal Cell
/
Kidney Neoplasms
/
Nephrectomy
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2017
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Peking University First Hospital/CN
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