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Distribution and morphology of ghrelin-immunopositive cells in the liver of the African ostrich / Distribución y morfología de las células inmunopositivas a la gregina en el hígado de avestruz africana
Jia-xiang, Wang; Peng, Li; Xiao-ting, Zhang; Li-xun, Ye.
  • Jia-xiang, Wang; Yangtze University. College of Animal Science. Jingzhou. CN
  • Peng, Li; Yangtze University. College of Animal Science. Jingzhou. CN
  • Xiao-ting, Zhang; Yangtze University. College of Animal Science. Jingzhou. CN
  • Li-xun, Ye; Yangtze University. College of Animal Science. Jingzhou. CN
Int. j. morphol ; 35(4): 1285-1290, Dec. 2017. graf
Article in English | LILACS | ID: biblio-893129
ABSTRACT

SUMMARY:

Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor, and has been found in the liver of multiple vertebrates. While ghrelin has been identified in the gastrointestinal tract of African ostrich chicks, little is known regarding its distribution in the liver of the African ostrich. In the present study, the distribution and morphological characteristics of ghrelin-immunopositive (ghrelin-ip) cells in the liver of the African ostrich were investigated using immunohistochemistry. Our results indicate that the liver is divided into two sections the capsule and the parenchyma, which comprises hepatic lobules and the hepatic portal area. The hepatic lobules include the central vein, hepatocellular cord, and the hepatic sinusoid. The hepatocellular cord is composed of hepatocytes, and Macrophagocytus stellatus (Kupffer cells) as well as endothelial cells reside within the hepatic sinusoid. ghrelin-ip cells were detected among both the Macrophagocytus stellatus and endothelial cells of the hepatic sinusoid in the African ostrich liver. In contrast, no ghrelinip cells were located within the hepatocytes or the hepatic portal area. These results clearly demonstrated the presence of ghrelin-ip cells in the liver of the African ostrich. Therefore, ghrelin may have a physiological function in the liver of the African ostrich.
RESUMEN
RESUMEN La ghrelina es el ligando endógeno para el receptor secretagogo de la hormona del crecimiento, y se ha encontrado en el hígado de múltiples vertebrados. A pesar que la ghrelina ha sido identificada en el tracto gastrointestinal de polluelos de avestruz africanas, poco se sabe sobre su distribución en el hígado de esta ave. En el presente estudio se investigó la distribución y características morfológicas de las células ghrelininmunopositivas (ghrelin-ip) en el hígado del avestruz africana mediante inmunohistoquímica. Nuestros resultados indican que el hígado se divide en dos secciones la cápsula y el parénquima, que comprende los lóbulos hepáticos y el área portal hepática. Los lóbulos hepáticos incluyen la vena central, el cordón hepatocelular y el sinusoide hepático. El cordón hepatocelular está compuesto de hepatocitos y de Macrophagocytus stellatus (células de Kupffer) y las células endoteliales se localizan dentro del sinusoide hepático. Fueron detectacas células ghrelin-ip entre los Macrophagocytus stellatus y las células endoteliales del sinusoide hepático en el hígado de avestruz africana. En contraste, no se localizaron células de ghrelin-ip dentro de los hepatocitos o en el área portal hepática. Estos resultados demuestran claramente la presencia de células de ghrelin-ip en el hígado. Por lo tanto, la ghrelina puede tener una función fisiológica en el hígado de avestruz africana.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Struthioniformes / Ghrelin / Liver Type of study: Prognostic study Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2017 Type: Article / Project document Affiliation country: China Institution/Affiliation country: Yangtze University/CN

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Full text: Available Index: LILACS (Americas) Main subject: Struthioniformes / Ghrelin / Liver Type of study: Prognostic study Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2017 Type: Article / Project document Affiliation country: China Institution/Affiliation country: Yangtze University/CN