Oral cancer stem cells - properties and consequences
J. appl. oral sci
;
25(6): 708-715, Nov.-Dec. 2017. graf
Article
in English
| LILACS, BBO
| ID: biblio-893672
ABSTRACT
Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Neoplastic Stem Cells
/
Mouth Neoplasms
/
Carcinoma, Squamous Cell
Limits:
Humans
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade de São Paulo/BR
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