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Risk factors for hepatitis B transmission in South Brazil
Pereira, Vagner Reinaldo Zingalli Bueno; Wolf, Jonas Michel; Luz, Camila Albani da Silva; Stumm, Gláucia Zuleide; Boeira, Thais da Rocha; Galvan, Josiane; Simon, Daniel; Lunge, Vagner Ricardo.
  • Pereira, Vagner Reinaldo Zingalli Bueno; Universidade Luterana do Brasil. Canoas. BR
  • Wolf, Jonas Michel; Universidade Luterana do Brasil. Canoas. BR
  • Luz, Camila Albani da Silva; Universidade Luterana do Brasil. Canoas. BR
  • Stumm, Gláucia Zuleide; Universidade Luterana do Brasil. Canoas. BR
  • Boeira, Thais da Rocha; Universidade Luterana do Brasil. Canoas. BR
  • Galvan, Josiane; Universidade Luterana do Brasil. Canoas. BR
  • Simon, Daniel; Universidade Luterana do Brasil. Canoas. BR
  • Lunge, Vagner Ricardo; Universidade Luterana do Brasil. Canoas. BR
Mem. Inst. Oswaldo Cruz ; 112(8): 544-550, Aug. 2017. tab
Article in English | LILACS | ID: biblio-894870
ABSTRACT
BACKGROUND Hepatitis B virus (HBV) infection is a major public health problem in Brazil. Several risk factors are involved in HBV infection and their identification by a rational and essential approach is required to prevent the transmission of this infection in Brazil. OBJECTIVES To evaluate risk factors associated with HBV infection in South Brazil. METHODS A total of 260 patients with HBV and 260 controls from Caxias do Sul (state of Rio Grande do Sul, Brazil) participated in this study. All participants were given a standard questionnaire to yield the sociodemographic information and to identify HBV risk factors. HBV infection was detected by HBsAg test in all participants. FINDINGS HBV infection in these cases was strongly associated with history of a family member HBV-infected, mainly mother [odds ratio (OR) = 4.86; 95% confidence intervals (CI) 1.69-13.91], father (OR = 5.28; 95% CI 1.58-17.71), and/or siblings (OR = 22.16; 95% CI 9.39-52.25); sharing personal objects (OR = 1.40; 95% CI 1.37-2.38); and having history of blood transfusion (OR = 2.05; 95% CI 1.10-2.84). CONCLUSIONS HBV infection was strongly associated with having a family member infected with hepatitis B, sharing personal objects, and having history of blood transfusion.
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Full text: Available Index: LILACS (Americas) Main subject: Hepatitis B virus / Hepatitis B, Chronic / Hepatitis B Antibodies / Hepatitis B Surface Antigens Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Luterana do Brasil/BR

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Full text: Available Index: LILACS (Americas) Main subject: Hepatitis B virus / Hepatitis B, Chronic / Hepatitis B Antibodies / Hepatitis B Surface Antigens Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Luterana do Brasil/BR