Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome
Mem. Inst. Oswaldo Cruz
;
113(7): e180050, 2018.
Article
in English
| LILACS
| ID: biblio-894943
ABSTRACT
Cryptococcosis diagnosis has been recently improved by the use of rapid cryptococcal antigen testing with lateral flow assays, which have proved sensitive and specific. Using "test and treat" screening strategies for cryptococcal disease with these tests has been showed effective in reducing cryptococcal meningitis (CM) in HIV-infected patients. Recommended induction, consolidation, and maintenance therapeutic strategy for CM is widely unavailable and/or expensive in low and middle-income settings. New therapeutic strategies, mostly using reduced duration, have recently shown acceptable outcome or are currently tested. Diagnostic and therapeutic guidelines for cryptococcal disease in limited resources countries are undergoing a paradigmatic shift.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Meningitis, Cryptococcal
/
AIDS-Related Opportunistic Infections
/
Cryptococcosis
Type of study:
Diagnostic study
/
Practice guideline
Limits:
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2018
Type:
Article
Affiliation country:
France
Institution/Affiliation country:
Institut Pasteur/FR
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