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Use of transfer factor in immunosuppressed surgical patients / Avaliação do uso de fator de transferência na resposta imunológica de pacientes cirúrgicos imunodeprimidos
Garritano, Celia Regina Oliveira; Nubila, Francesco di; Couto, Renata M; Fiorelli, Rossano Kepler Alvim; Aun, Luciana Berti.
  • Garritano, Celia Regina Oliveira; Federal University of the State of Rio de Janeiro. Department of General and Specialized Surgery. Rio de Janeiro. BR
  • Nubila, Francesco di; Federal University of the State of Rio de Janeiro. Department of General and Specialized Surgery. Rio de Janeiro. BR
  • Couto, Renata M; Federal University of the State of Rio de Janeiro. Department of General and Specialized Surgery. Rio de Janeiro. BR
  • Fiorelli, Rossano Kepler Alvim; Federal University of the State of Rio de Janeiro. Department of General and Specialized Surgery. Rio de Janeiro. BR
  • Aun, Luciana Berti; Federal University of the State of Rio de Janeiro. Department of General and Specialized Surgery. Rio de Janeiro. BR
Rev. Col. Bras. Cir ; 44(5): 452-456, Sept.-Oct. 2017. tab, graf
Article in English | LILACS | ID: biblio-896606
ABSTRACT
ABSTRACT

Objective:

to evaluate the action of Transfer Factor on the immune response of patients with malignant neoplasm submitted to surgery, chemotherapy and radiotherapy.

Method:

we analyzed the variations of leukocytes, total lymphocytes, T-lymphocytes and CD4 counts in 60 patients submitted to immunostimulation with a single, daily dose of 0.5mg sublingual Transfer Factor, started simultaneously with chemotherapy and/or radiotherapy.

Results:

there were statistically significant increases in the counts of all cell lines studied, more pronounced after 12 months of use of the medication.

Conclusion:

the Transfer Factor restored immune response and showed no side effects.
RESUMO
RESUMO

Objetivo:

avaliar a ação do Fator de Transferência na resposta imunológica de pacientes portadores de neoplasia maligna submetidos à cirurgia, quimioterapia e radioterapia.

Método:

análise das variações dos valores dos leucócitos, linfócitos totais, linfócitos T e CD4 em 60 pacientes submetidos à imunoestimulação com Fator de Transferência administrado em dose única de 0,5mg por via sublingual, diariamente e iniciada simultaneamente à quimioterapia e/ou radioterapia.

Resultados:

houve um aumento no número de todas as linhagens celulares estudadas que foi mais acentuada após 12 meses de uso da medicação. A análise estatística realizada com o software Graph Pad Instat, testadas pelo método Kolmogorov and Smirnov, mostrou que os resultados foram significativos.

Conclusão:

o Fator de Transferência restabeleceu a resposta imune e não apresentou efeitos colaterais.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Transfer Factor / Immunocompromised Host / Neoplasms Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of the State of Rio de Janeiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Transfer Factor / Immunocompromised Host / Neoplasms Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of the State of Rio de Janeiro/BR