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Sofosbuvir and daclatasvir combination therapy for current hepatitis C virus genotype 4 achieves SVR: a case report of HCV genotype 4 from the Amazon
Tarragô, Andréa Monteiro; Pereira, Grenda Leite; Victória, Flamir da Silva; Marie, Adriana Malheiro Alle; Victória, Marilú Barbieri.
Affiliation
  • Tarragô, Andréa Monteiro; Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Laboratório de Genômica. Manaus. BR
  • Pereira, Grenda Leite; Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Laboratório de Genômica. Manaus. BR
  • Victória, Flamir da Silva; Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Laboratório de Genômica. Manaus. BR
  • Marie, Adriana Malheiro Alle; Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Laboratório de Genômica. Manaus. BR
  • Victória, Marilú Barbieri; Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Laboratório de Genômica. Manaus. BR
Rev. Soc. Bras. Med. Trop ; 50(6): 861-863, Nov.-Dec. 2017. tab
Article in En | LILACS | ID: biblio-897030
Responsible library: BR1.1
ABSTRACT
Abstract Hepatitis C is a worldwide endemic disease. However, hepatitis C virus genotype 4 (HCV GT-4) has rarely been reported in Brazil. HCV GT-4 demonstrates high sustained virological response (SVR). Here, we report the case of a 62-year-old HCV GT-4 positive woman complaining of a headache, nausea, and arthralgia. The patient was treated according to the protocol for genotype 4 (12 weeks administration of 400mg sofosbuvir and 60mg daclatasvir daily) and achieved SVR. Although this is not an Amazonas autochthonous case, the presence of genotype 4 is rarely reported in the region.
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Full text: 1 Index: LILACS Main subject: Antiviral Agents / Hepatitis C, Chronic / Sofosbuvir / Imidazoles Limits: Female / Humans Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2017 Type: Article
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Full text: 1 Index: LILACS Main subject: Antiviral Agents / Hepatitis C, Chronic / Sofosbuvir / Imidazoles Limits: Female / Humans Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2017 Type: Article