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Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
Covre, Lúcia Carla Polaco; Hombre, Pâmela Mazzini; Falqueto, Aloísio; Peçanha, Paulo Mendes; Valim, Valéria.
Affiliation
  • Covre, Lúcia Carla Polaco; Universidade Federal do Espírito Santo. Hospital Universitário Cassiano Antônio Moraes. Curso de Medicina. Vitória. BR
  • Hombre, Pâmela Mazzini; Universidade Federal do Espírito Santo. Hospital Universitário Cassiano Antônio Moraes. Curso de Medicina. Vitória. BR
  • Falqueto, Aloísio; Universidade Federal do Espírito Santo. Hospital Universitário Cassiano Antônio Moraes. Curso de Medicina. Vitória. BR
  • Peçanha, Paulo Mendes; Universidade Federal do Espírito Santo. Hospital Universitário Cassiano Antônio Moraes. Curso de Medicina. Vitória. BR
  • Valim, Valéria; Universidade Federal do Espírito Santo. Hospital Universitário Cassiano Antônio Moraes. Curso de Medicina. Vitória. BR
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;51(2): 249-252, Mar.-Apr. 2018. tab, graf
Article in En | LILACS | ID: biblio-897059
Responsible library: BR1.1
ABSTRACT
Abstract Paracoccidioidomycosis is an endemic disease in Latin America that is rarely associated with immunosuppression and biological therapy. Herein, we report for the first time a case of pulmonary paracoccidioidomycosis reactivation after infliximab treatment. A 47-year-old man from Brazil received infliximab to treat psoriatic spondyloarthropathy and presented with cough, dyspnea, weight loss, and fever. Chest computed tomography revealed a pulmonary nodule and biopsy confirmed paracoccidioidomycosis. Treatment with sulfamethoxazole and trimethoprim was initiated for fungal infection and infliximab was reintroduced two months later. Considering his clinical improvement and favorable radiologic evolution, antifungal therapy was discontinued after 29 months.
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Full text: 1 Index: LILACS Main subject: Paracoccidioidomycosis / Antirheumatic Agents / Infliximab / Lung Diseases, Fungal Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2018 Type: Article
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Full text: 1 Index: LILACS Main subject: Paracoccidioidomycosis / Antirheumatic Agents / Infliximab / Lung Diseases, Fungal Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2018 Type: Article