Effectiveness of implantation of cardioverter-defibrillators therapy in patients with non-ischemic heart failure: an updated systematic review and meta-analysis
Rev. bras. cir. cardiovasc
;
32(5): 417-422, Sept.-Oct. 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-897939
ABSTRACT
Abstract Objective:
Implantable cardioverter-defibrillator has become the first-line therapy for prevention of sudden cardiac death. Controversial results still exist regarding the effectiveness of implantable cardioverter-defibrillator (ICD) in non-ischemic heart failure.Methods:
The PubMed, Embase, and Cochrane Central databases were searched for randomized trials comparing implantable cardioverter-defibrillator in combination with medical treatment versus medical treatment for non-ischemic heart failure. The primary endpoint was incidence of all-cause death. We derived pooled risk ratios with fixed-effects models.Results:
Five studies enrolling 2573 patients were included. Compared with medical treatment, implantable cardioverter-defibrillator with medical treatment was associated with a significantly lower risk for all-cause mortality (Risk ratio 0.83; 95% confidence interval 0.71 to 0.97).Conclusion:
Compared with medical treatment only, implantable cardioverter-defibrillator in combination with medical treatment reduces all-cause mortality.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Defibrillators, Implantable
/
Heart Failure
Type of study:
Controlled clinical trial
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Rev. bras. cir. cardiovasc
Journal subject:
Cardiology
/
General Surgery
Year:
2017
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Central South University/CN
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