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Effectiveness of implantation of cardioverter-defibrillators therapy in patients with non-ischemic heart failure: an updated systematic review and meta-analysis
Xing, Zhenhua; Tang, Liang; Chen, Chenyang; Huang, Jiabing; Zhu, Zhaowei; Hu, Xinqun.
  • Xing, Zhenhua; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
  • Tang, Liang; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
  • Chen, Chenyang; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
  • Huang, Jiabing; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
  • Zhu, Zhaowei; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
  • Hu, Xinqun; Central South University. Second Xiangya Hospital. Department of Cardiology. Huan Province. CN
Rev. bras. cir. cardiovasc ; 32(5): 417-422, Sept.-Oct. 2017. tab, graf
Article in English | LILACS | ID: biblio-897939
Responsible library: BR1.1
ABSTRACT
Abstract

Objective:

Implantable cardioverter-defibrillator has become the first-line therapy for prevention of sudden cardiac death. Controversial results still exist regarding the effectiveness of implantable cardioverter-defibrillator (ICD) in non-ischemic heart failure.

Methods:

The PubMed, Embase, and Cochrane Central databases were searched for randomized trials comparing implantable cardioverter-defibrillator in combination with medical treatment versus medical treatment for non-ischemic heart failure. The primary endpoint was incidence of all-cause death. We derived pooled risk ratios with fixed-effects models.

Results:

Five studies enrolling 2573 patients were included. Compared with medical treatment, implantable cardioverter-defibrillator with medical treatment was associated with a significantly lower risk for all-cause mortality (Risk ratio 0.83; 95% confidence interval 0.71 to 0.97).

Conclusion:

Compared with medical treatment only, implantable cardioverter-defibrillator in combination with medical treatment reduces all-cause mortality.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Defibrillators, Implantable / Heart Failure Type of study: Controlled clinical trial / Systematic reviews Limits: Humans Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / General Surgery Year: 2017 Type: Article Affiliation country: China Institution/Affiliation country: Central South University/CN

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Full text: Available Index: LILACS (Americas) Main subject: Defibrillators, Implantable / Heart Failure Type of study: Controlled clinical trial / Systematic reviews Limits: Humans Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / General Surgery Year: 2017 Type: Article Affiliation country: China Institution/Affiliation country: Central South University/CN