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Three cases of anti-TNF induced myositis and literature review / Três casos de miosite induzida pelo anti-TNF e revisão da literatura
Zengin, Orhan; Onder, Mustafa Erkut; Alkan, Samet; Kimyon, Gezmiş; Hüseynova, Nergis; Demir, Zeynep Hanım; Kısacık, Bünyamin; Onat, Ahmet Mesut.
  • Zengin, Orhan; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Onder, Mustafa Erkut; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Alkan, Samet; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Kimyon, Gezmiş; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Hüseynova, Nergis; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Demir, Zeynep Hanım; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Kısacık, Bünyamin; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
  • Onat, Ahmet Mesut; Gaziantep University. School of Medicine. Department of Rheumatology. Gaziantep. TR
Rev. bras. reumatol ; 57(6): 590-595, Nov.-Dec. 2017. tab
Article in English | LILACS | ID: biblio-899480
ABSTRACT
Abstract Anti-tumor necrosis factor drugs are frequently preferred in the treatment of rheumatologic diseases and other inflammatory diseases. The development of myositis after using anti-tumor necrosis factor drugs is a rare clinical condition. Here we aimed to report cases who developed myositis after using anti-tumor necrosis factor drugs and review the current literature. We report two cases of rheumatoid arthritis and a case of ankylosing spondylitis developed idiopathic inflammatory myopathy following anti-tumor necrosis factor therapy. In conclusion, myositis could develop during anti-tumor necrosis factor therapy, so these patients should be evaluated carefully initially for myositis and should be closely monitored due to the potential for developing myositis in treatment process.
RESUMO
Resumo Os fármacos antifator de necrose tumoral (anti-TNF) são frequentemente preferidos no tratamento de doenças reumatológicas e outras doenças inflamatórias. O desenvolvimento de miosite após o uso de anti-FNT é uma condição clínica rara. Este estudo objetivou descrever casos de pacientes que desenvolveram miosite após o uso de anti-TNF e fazer uma revisão da literatura atual. Descrevem-se dois casos de artrite reumatoide (AR) e um caso de espondilite anquilosante (EA) que desenvolveram miopatia inflamatória idiopática após o tratamento com anti-TNF. Em conclusão, pode haver desenvolvimento de miosite durante o tratamento com anti-TNF, de modo que esses pacientes devem ser cuidadosamente avaliados inicialmente à procura de miosite e devem ser cuidadosamente monitorados em razão do potencial de desenvolvimento de miosite no processo de tratamento
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Tumor Necrosis Factor-alpha / Antirheumatic Agents / Adalimumab / Etanercept / Myositis Type of study: Diagnostic study Limits: Adolescent / Female / Humans / Male Language: English Journal: Rev. bras. reumatol Journal subject: Rheumatology Year: 2017 Type: Article Affiliation country: Turkey Institution/Affiliation country: Gaziantep University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Tumor Necrosis Factor-alpha / Antirheumatic Agents / Adalimumab / Etanercept / Myositis Type of study: Diagnostic study Limits: Adolescent / Female / Humans / Male Language: English Journal: Rev. bras. reumatol Journal subject: Rheumatology Year: 2017 Type: Article Affiliation country: Turkey Institution/Affiliation country: Gaziantep University/TR