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Nuevos progresos en el enfrentamiento a la hepatitis C / New progresses in hepatitis C management
Arredondo Bruce, Alfredo Enrique; Prez Trujillo, Ion.
  • Arredondo Bruce, Alfredo Enrique; Hospital Provincial Docente Amalia Simoni. Camagüey. CU
  • Prez Trujillo, Ion; Hospital Provincial Docente Amalia Simoni. Camagüey. CU
Rev. medica electron ; 40(2): 383-393, mar.-abr. 2018. ilus
Article in Spanish | LILACS, CUMED | ID: biblio-902306
RESUMEN
RESUMEN El virus de la hepatitis C es la principal infección trasmitida por los derivados de la sangre en los Estados Unidos, con 3.2 millones de individuos infectados. El alfa interferón inyectable ha sido históricamente la piedra angular en la terapia del virus de hepatitis C. Se revisaron las publicaciones los trabajos publicados en Medline, Scielo, PubMed, e Hinari, hasta comienzos del año 2016. Las principales palabras clave utilizadas fueron virus de la hepatitis C, hepatitis C crónica, Interferón, antivirales. Recientes adelantos han llevado a la disponibilidad de nuevos medicamentos antivirales, que con el desarrollo de nuevas terapias orales libres de interferón han convertido la terapia del virus de la hepatitis C más eficaz además de simplificar los regímenes del tratamiento. Aunque estos regímenes de tratamiento aún permanecen complicados, las nuevas recomendaciones y guías evolucionan rápidamente. El rápido desarrollo de nuevas terapias para la hepatitis C, han logrado métodos más eficaces con menos reacciones adversas que optimizan el tratamiento de estos enfermos (AU).
ABSTRACT
ABSTRACT The hepatitis C virus is the main infection transmitted by blood products in the United States, with 3.2 million of infected individuals. The injected alpha interferon has historically been the key stone in the therapy of the hepatitis C virus. The works published in Medline, Scielo, PubMed and Hinary until the beginning of 2016 were reviewed. The main used key words were HVC, cronic hepatitis C, interferon, antivirals. Recent advances have led to the availability on new antiviral drugs, developing new interferon-free oral therapies that make the therapy of hepatitis C virus more efficacious and make easier the treatment regimens. Although these treatment regimens are still complicated, the new recommendations and guidelines evolve quickly. The fast development of new therapies against hepatitis C has led to more efficacious methods with less adverse reactions, optimizing the treatment of these patients (AU).
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Virology / Risk Factors / Interferon-alpha / Hepacivirus / Hepatitis C, Chronic / Epidemiological Monitoring Type of study: Diagnostic study / Etiology study / Practice guideline / Risk factors / Screening study Limits: Humans Country/Region as subject: North America / Caribbean / Cuba Language: Spanish Journal: Rev. medica electron Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Provincial Docente Amalia Simoni/CU

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Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Virology / Risk Factors / Interferon-alpha / Hepacivirus / Hepatitis C, Chronic / Epidemiological Monitoring Type of study: Diagnostic study / Etiology study / Practice guideline / Risk factors / Screening study Limits: Humans Country/Region as subject: North America / Caribbean / Cuba Language: Spanish Journal: Rev. medica electron Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Provincial Docente Amalia Simoni/CU