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Prevalencia de esteatosis hepática no alcohólica en pacientes diabéticos tipo 2, con o sin síndrome metabólico / Prevalence of non alcoholic hepatic steatosis in diabetic patients type 2, with or without metabolic syndrome
Sanjinez Asbún, Marcia; Nishi, Carlos; López Bilbao La Vieja, Ignacio; Urquizo Ayala, Guillermo.
  • Sanjinez Asbún, Marcia; Hospital de Clínicas Universitario. La Paz. BO
  • Nishi, Carlos; Hospital de Clínicas Universitario. La Paz. BO
  • López Bilbao La Vieja, Ignacio; Hospital de Clínicas Universitario. La Paz. BO
  • Urquizo Ayala, Guillermo; Hospital de Clínicas Universitario. La Paz. BO
Rev. méd. (La Paz) ; 23(1): 12-18, 2017. ilus
Article in Spanish | LILACS, LIBOCS | ID: biblio-902416
RESUMEN
Recientemente se ha establecido a la esteatosis hepática no alcohólica (EHNA) como un componente más del síndrome metabólico, predictor del desarrollo de diabetes mellitus tipo 2. De los pacientes con EHNA y fibrosis leve a moderada, aproximadamente 13% desarrollan cirrosis en el curso de 4 años. Conocer la prevalencia de esta entidad en población de riesgo de nuestro medio, favorecería tomar algunas conductas diagnósticas y terapéuticas en forma oportuna.

OBJETIVO:

determinar la prevalencia de esteatosis hepática no alcohólica en pacientes con diabetes mellitus tipo 2. MATERIAL Y

METODOS:

estudio de corte transversal, que incluye a 95 pacientes con diagnóstico establecido de diabetes mellitus tipo 2, con o sin síndrome metabólico. Se les realizó medición de peso, talla, IMC, perímetro de cintura, área de grasa visceral y porcentaje de grasa corporal mediante impedanciometría, ecografía hepática y glicemia basal. Se realizó el análisis estadístico mediante el paquete S.P.S.S. para Windows, versión 12.0.

RESULTADOS:

del total de 95 pacientes diabéticos tipo 2 estudiados, 22% (21) fueron varones y 78% (74) mujeres, comprendidos entre los 25 a 74 años, de los cuales 58.9% (56) eran portadores de síndrome metabólico según los criterios de ATP III. 26.3 % (25) pacientes no tenían alteraciones ecográficas compatibles con esteatosis hepática. Presentaron esteatosis leve o grado 1 el 16.8 % (16), 48.4% esteatosis moderada o grado 2, y finalmente 8.4% (8) con esteatosis severa o grado 3.

CONCLUSIONES:

la prevalencia de esteatosis hepática no alcohólica, diagnosticada mediante ecografía hepática en los pacientes diabéticos de tipo 2 es del 74%, independientemente del diagnóstico de síndrome metabólico, lo que incrementa el riesgo de complicaciones en estos pacientes.
ABSTRACT
Has recently been established to non-alcoholic hepatic steatosis as one component of metabolic syndrome, predictor of the development of type 2 diabetes mellitus. Patients with NAFLD and mild to moderate fibrosis, approximately 13% develop cirrhosis in the course of 4 years. So you know the prevalence of this institution at risk for our country, it would take some conduct diagnostic and therapeutic in a timely manner.

OBJECTIVE:

To determine the prevalence of non-alcoholic fatty liver in patients with diabetes mellitus type 2.

METHODS:

Cross-sectional study, prospective, descriptive, observational and analytical, cut that includes 95 patients with an established diagnosis of diabetes mellitus type 2, with or without metabolic syndrome. He was performed in measurement of weight, height, BMI, perimeter of waist, visceral fat and percentage of body fat by impedance measurement and liver ultrasound and basal glycaemia. He was the statistical analysis using the S.P.S.S. for Windows, version 12.0 package.

RESULTS:

Of the total of 95 patients diabetic type 2 studied, 22% (21) were males and 78% (74) women, between 25 to 74 years, of which 58.9% (56) were carriers of metabolic syndrome according to the ATP III criteria. 26.3% (25) patients had no alterations compatible with fatty liver ultrasound. They presented mild steatosis or grade 1 the 16.8% (16), 48.4% steatosis moderate grade 2, and finally 8.4% (8) with severe steatosis or grade 3.

CONCLUSIONS:

the prevalence of non-alcoholic fatty liver, diagnosed by liver ultrasound in type 2 diabetic patients is 74 percent, which increases the risk of complications in these patients.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Diabetes Mellitus / Non-alcoholic Fatty Liver Disease Type of study: Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Limits: Humans Language: Spanish Journal: Rev. méd. (La Paz) Journal subject: Medicine Year: 2017 Type: Article Affiliation country: Bolivia Institution/Affiliation country: Hospital de Clínicas Universitario/BO

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Full text: Available Index: LILACS (Americas) Main subject: Diabetes Mellitus / Non-alcoholic Fatty Liver Disease Type of study: Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Limits: Humans Language: Spanish Journal: Rev. méd. (La Paz) Journal subject: Medicine Year: 2017 Type: Article Affiliation country: Bolivia Institution/Affiliation country: Hospital de Clínicas Universitario/BO