Adenovirus 36 y su potencial contribución en el desarrollo de obesidad / The potential contribution of adenovirus 36 to the development of obesity
Rev. méd. Chile
;
145(8): 1054-1059, ago. 2017.
Article
in Spanish
| LILACS
| ID: biblio-902584
ABSTRACT
The evidence of the last 20 years shows a link between viral infections and obesity in animals and humans. There are five adenovirus which have been associated with development of obesity in animals. SMAM-1 virus was the first studied in humans associated with obesity. There is compelling evidence that Ad-36 virus could contribute to the development of obesity in humans and it is related with body mass index (BMI). This manuscript reviews the association between Ad-36 and the other four virus infections with obesity. An electronic search of articles in the databases PubMed and Scielo, with use of key words obesity, infection, adipose tissue, Ad-36, 3T3-L1 was performed. The search was restricted "human" and "animals". The importance of the relationship between virus infections and obesity has increased over the past two decades. Ad-36 shows more compelling evidence in humans. There are reports involving this virus in the enhancement of adipogenesis, adipocyte differentiation, a lower secretion of leptin and an increased insulin sensitivity. Future work should focus in larger cohort studies to confirm this association, which explains the global obesity epidemic from a new perspective.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adenoviridae
/
Adenoviridae Infections
/
Obesity
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Animals
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2017
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad Bernardo O'Higgins/CL
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