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Hepatitis C: evaluation of outcomes and georeferencing of cases in Santa Cruz do Sul, Brazil, between 2002 and 2015. A cross-sectional study
Possuelo, Lia Goncalves; Perin, Daiane; Breunig, Patricia Faber; Schroeder, Daniel Felipe; Allgayer, Manuela Filter; Darsie, Camilo; Carneiro, Marcelo; Hermes, Vanda; Renner, Jane Dagmar Pollo.
  • Possuelo, Lia Goncalves; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Perin, Daiane; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Breunig, Patricia Faber; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Schroeder, Daniel Felipe; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Allgayer, Manuela Filter; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Darsie, Camilo; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Carneiro, Marcelo; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Hermes, Vanda; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
  • Renner, Jane Dagmar Pollo; Universidade de Santa Cruz do Sul. Department of Biology and Pharmacy. Santa Cruz do Sul. BR
São Paulo med. j ; 136(2): 109-115, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-904153
ABSTRACT
ABSTRACT

BACKGROUND:

Hepatitis C virus infection is one of the main causes of chronic liver disease, with high death rates. The aim here was to analyze case outcomes, sociodemographic and clinical characteristics and spatial distribution among patients diagnosed with hepatitis C in the city of Santa Cruz do Sul (RS), Brazil. DESIGN AND

SETTING:

Cross-sectional study on 200 cases of hepatitis C in Santa Cruz do Sul that were notified between 2002 and 2015.

METHODS:

Secondary data including sociodemographic and clinical variables and type of outcome (death, follow-up, abandonment or clinical cure) were gathered. The spatial distribution analysis on hepatitis C virus cases according to outcome was based on information regarding residential address.

RESULTS:

58.5% of the patients were 41 years of age and over, 67% were males and 92.5% had the chronic form of the disease. The most frequent transmission route was illicit drug injection (29%); 15.1% of the patients presented coinfection with the human immunodeficiency virus (HIV). Regarding outcomes, 31% achieved clinical cure, 10% died and 20% abandoned follow-up. The cases studied were mainly located in regions of the city characterized by lower socioeconomic status, with high frequency of places used for drug trafficking.

CONCLUSION:

The population consisted of adults aged 41 years and over, mostly with chronic hepatitis C. The most common transmission routes were illicit drug injection and blood transfusions. There were high rates of HIV coinfection and abandonment of disease monitoring and predominance of cases in neighborhoods with low socioeconomic status.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Hepatitis C, Chronic Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Santa Cruz do Sul/BR

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Full text: Available Index: LILACS (Americas) Main subject: Hepatitis C, Chronic Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Santa Cruz do Sul/BR