Your browser doesn't support javascript.
loading
Morphological alterations and time-kill studies of the essential oil from the leaves of Coriandrum sativum L. on Candida albicans / Alteraciones morfológicas y estudios de letalidad del aceite esencial de las hojas de Coriandrum sativum L. en Candida albicans
Sousa, Janiere P; Queiroz, Everton O; Guerra, Felipe Q. S; Mendes, Juliana M; Pedrosa, Zilmara V; Filho, Abrahão A. O; Pereira, Fillipe O; Trajano, Vinicius N; Souza, Fábio S; Lima, Edeltrudes O.
  • Sousa, Janiere P; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Queiroz, Everton O; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Guerra, Felipe Q. S; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Mendes, Juliana M; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Pedrosa, Zilmara V; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Filho, Abrahão A. O; Federal University of Campina Grande. Academic Unit Biological Sciences. Patos. BR
  • Pereira, Fillipe O; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Trajano, Vinicius N; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Souza, Fábio S; Federal University of Paraíba. Department of Pharmaceutical Sciences. Unified Laboratory of Pharmaceutical Development and Assay. João Pessoa. BR
  • Lima, Edeltrudes O; Federal University of Paraíba. Department of Pharmaceutical Sciences. João Pessoa. BR
Bol. latinoam. Caribe plantas med. aromát ; 15(6): 398-406, nov. 2016. tab, ilus, graf
Article in English | LILACS | ID: biblio-907555
ABSTRACT
The objective of this study was to evaluate the morphological alterations and time-kill of the essential oil of the leaves of C. sativum L. on strains of C. albicans. The essential oil was submitted to gas chromatography-mass spectrometry analysis. The predominant component identified was linalool (39.78 percent). Minimal inhibitory concentration and minimal fungicidal concentration of the essential oil were respectively 512 and 1024 ug.mL-1 for 90 percent of the strains tested. In the time-kill curves, the essential oil showed a concentration-dependent fungicidal effect. In the micromorphology assay it caused a significant reduction in pseudohyphae, an important pathogenic factor of C. albicans.
RESUMEN
El objetivo de este estudio fue evaluar las alteraciones morfológicas y de letalidad del aceite esencial de las hojas de C. sativum L. en cepas de C. albicans. El aceite esencial se presentó a gas análisis de espectrometría de cromatografía-masa. El componente predominante identificado fue linalol (39,78 por ciento). Concentración inhibitoria mínima y concentración mínima fungicida del aceite esencial fueron, respectivamente, 512 y 1.024 ìg.mL-1 para 90 por ciento de las cepas probadas. En las curvas el tiempo-matar, el aceite esencial mostró un efecto fungicida dependiente de la concentración. En el ensayo de micromorfología causó una reducción significativa en pseudohifas, un importante factor patógeno de C. albicans.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Candida albicans / Oils, Volatile / Plant Leaves / Coriandrum / Antifungal Agents Type of study: Prognostic study Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Campina Grande/BR / Federal University of Paraíba/BR

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: LILACS (Americas) Main subject: Candida albicans / Oils, Volatile / Plant Leaves / Coriandrum / Antifungal Agents Type of study: Prognostic study Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Campina Grande/BR / Federal University of Paraíba/BR