Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. systematic review and meta-analysis
J. oral res. (Impresa)
;
6(5): 127-135, May 2017. ilus, tab
Article
in English
| LILACS
| ID: biblio-907733
ABSTRACT
Background:
There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs). One of the current options is the use of platelet-rich fibrin (PRF).Objective:
To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis. Materials andMethods:
A literature search was conducted up to February 2017 in the following biomedical databases Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials. The selection criteria included randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession), with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference.Results:
The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration.Conclusion:
The literature suggests that the use of PRF in the treatment of PIDs has a beneficial clinical effect when compared to control treatments.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Periodontitis
/
Fibrin
/
Platelet-Rich Plasma
/
Gingival Recession
Type of study:
Controlled clinical trial
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
J. oral res. (Impresa)
Journal subject:
Dentistry
Year:
2017
Type:
Article
Affiliation country:
Peru
Institution/Affiliation country:
Universidad Católica los Ángeles de Chimbote/PE
/
Universidad Nacional de Trujillo/PE
/
Universidad Particular de Chiclayo/PE
/
Universidad Privada Antonio Guillermo Urrelu/PE
/
Universidad San Martín de Porres/PE
/
Universidad Señor de Sipán/PE
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