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Liquid biopsy: emergence of a new era in personalized cancer care
Abraham, J; Singh, S; Joshi, S.
  • Abraham, J; All India Institute of Medical Sciences. Department of Biochemistry. Raipur. IN
  • Singh, S; All India Institute of Medical Sciences. Department of Biochemistry. Raipur. IN
  • Joshi, S; All India Institute of Medical Sciences. Department of Biochemistry. Raipur. BR
Appl. cancer res ; 38: 1-17, jan. 30, 2018. tab, ilus
Article in English | LILACS, Inca | ID: biblio-910469
ABSTRACT
The most successful treatment for cancer involves identifying druggable, biological markers for targeted therapy. In the clinical setting, surgical removal of tumors is the only procedure for identifying such targetable molecules. Shed from tumor cells, these markers are also present in circulating blood, albeit in very negligible amounts. Liquid biopsy is a procedure performed on a blood sample to look for such circulating cancer markers cells or pieces of nucleic acid from the tumor. The procedure shows promise in revolutionizing personalized cancer treatments. Here we briefly review the technique, characterization, and its utilization in clinics
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Full text: Available Index: LILACS (Americas) Main subject: Biomarkers / Molecular Targeted Therapy / Cell-Free Nucleic Acids / Liquid Biopsy / Neoplastic Cells, Circulating Limits: Humans Language: English Journal: Appl. cancer res Journal subject: Neoplasms Year: 2018 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/BR / All India Institute of Medical Sciences/IN

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Full text: Available Index: LILACS (Americas) Main subject: Biomarkers / Molecular Targeted Therapy / Cell-Free Nucleic Acids / Liquid Biopsy / Neoplastic Cells, Circulating Limits: Humans Language: English Journal: Appl. cancer res Journal subject: Neoplasms Year: 2018 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/BR / All India Institute of Medical Sciences/IN