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Radiographic Bone Evaluation after Periodontal Full Mouth Disinfection Treatment in Women Undergoing Chemotherapy or Hormone Therapy with Tamoxifen
Assis, Rahyza Inacio Freire de; Silva-Junior, Manoelito Ferreira; Santos, Marciel Silva dos; Pereira, Teresa Cristina Rangel; Feitosa, Alfredo Carlos Rodrigues; Azevedo-Vaz, Sergio Lins de.
  • Assis, Rahyza Inacio Freire de; s.af
  • Silva-Junior, Manoelito Ferreira; s.af
  • Santos, Marciel Silva dos; s.af
  • Pereira, Teresa Cristina Rangel; Federal University of Espírito Santo. BR
  • Feitosa, Alfredo Carlos Rodrigues; Federal University of Espírito Santo. Vitória. BR
  • Azevedo-Vaz, Sergio Lins de; Federal University of Espírito Santo. Vitória. BR
Pesqui. bras. odontopediatria clín. integr ; 16(1): 219-227, jan.-dez. 2016. tab, ilus
Article in English | LILACS, BBO | ID: biblio-912430
ABSTRACT

Objective:

To radiographically evaluate the alveolar bone level after periodontal full mouth disinfection (FMD) treatment in women during chemotherapy (CHE) and hormone therapy with Tamoxifen (TAM). Material and

Methods:

This is an uncontrolled clinical trial with a convenience sample of women in antineoplastic treatment (CHE and TAM) and non-surgical periodontal FMD treatment. The Radiographic examination consisted of four bitewing radiographs and six periapical radiographs of the upper and lower anterior teeth, acquired according to the parallelling standard technique at three times before (T0), 3 (T3) and 6 (T6) months after periodontal treatment. The alveolar crest level in the interproximal area of each tooth was measured by two calibrated observer using magnifying glass and digital caliper. Statistical analysis was performed for evaluation of the three times in each experimental group using the Friedman test (p < 0.05) and between groups, the Mann Whitney test (p <0.05).

Results:

Overall, 14 women undergoing treatment for breast cancer participated in this study. A follow-up loss of five (35.71%) women occurred during the study and the final sample size was composed of nine women divided into two groups CHE (n = 4) and TAM (n = 5). A total of 330 sites were evaluated 126 (CHE) and 204 (TAM). The alveolar bone level showed statistically significant reduction after 6 months of FMD therapy (p <0.05), but there was no difference between antineoplastic treatment type (p> 0.05).

Conclusion:

Patients undergoing chemotherapy and hormone therapy with Tamoxifen showed better alveolar bone levels after six months of periodontal FMD treatment. The current antineoplasic therapy did not influence the results obtained with periodontal treatment.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Oral Hygiene / Periodontal Diseases / Tamoxifen / Breast Neoplasms / Radiography, Dental Limits: Adult / Aged / Female / Humans Country/Region as subject: South America / Brazil Language: English Journal: Pesqui. bras. odontopediatria clín. integr Journal subject: Dentistry Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Espírito Santo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Oral Hygiene / Periodontal Diseases / Tamoxifen / Breast Neoplasms / Radiography, Dental Limits: Adult / Aged / Female / Humans Country/Region as subject: South America / Brazil Language: English Journal: Pesqui. bras. odontopediatria clín. integr Journal subject: Dentistry Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Espírito Santo/BR