Effect of sex on Toxocara canis larval migration to the cerebellum during experimental infection of Rattus norvegicus
Rev. patol. trop
;
47(2): 111-115, jun. 2018. tab
Article
in English
| LILACS
| ID: biblio-913770
ABSTRACT
The presence of Toxocara canis third instar larvae in the cerebellum of Rattus norvegicus may alter rodent behavior and movement. In this study, we investigated whether the sex of the rodent affects the migration of larvae to the cerebellum. Thirty-six Rattus norvegicus specimens (18 males and 18 females) were infected with 300 T. canis eggs and were euthanized after 60 days. The cerebellum was removed and treated with 0.5% HCl to recover the T. canis larvae. The number of larvae recovered from male rodents was significantly higher than in females, suggesting that the sex of the animal influences larval migration to the cerebellum
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Index:
LILACS (Americas)
Main subject:
Rats
/
Cerebellum
/
Toxocara canis
/
Larva
Limits:
Animals
Language:
English
Journal:
Rev. patol. trop
Journal subject:
Tropical Medicine
/
Pathology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Laboratório de Investigação Médica (LIM6), Instituto de Medicina Tropical da Universidade de São Paulo/BR
/
Laboratório de Parasitologia, Departamento de Ciências Patológicas da Faculdade de Ciências Médicas da Santa Casa de São Paulo/BR
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