Linking the platelet antiaggregation effect of different strawberries species with antioxidants: metabolomic and transcript profiling of polyphenols / Asociando el efecto de antiagregación plaquetaria de distintas especies de frutillas con antioxidantes: perfil metabolómico y transcriptómico de polifenoles
Bol. latinoam. Caribe plantas med. aromát
;
17(1): 36-52, ene. 2018. ilus, graf, tab
Article
in English
| LILACS
| ID: biblio-915054
ABSTRACT
A comparative study of antioxidant properties, platelet antiaggregation activity and transcriptional analysis of flavonoid biosynthesis genes were performed in Fragaria x ananassa, F. vesca and F. chiloensis subsp chiloensis f. chiloensis and f. patagonica. Furthermore, differences in flavonoid content were found by UHPLC-MS. The highest free radical scavenging activity by DPPH assay was observed in F. chiloensis f. chiloensis, meanwhile, F. vesca presented the highest antioxidant capacity by FRAP. Biosynthetic flavonoids- related transcripts were higher abundant in F. x ananassa and lower in F. vesca. Additionally, all strawberry extracts showed antiaggregant effect (1 mg mL-1), but F. vesca and F. chiloensis subsp. chiloensis f. patagonica were still active at lower concentration. This study suggests that platelet antiaggregation effect of different strawberries could be due to isoflavones and flavonoids precursors in addition to anthocyanins. Results could usefully to take decisions in future breeding programs to improve the content of healthy compounds in strawberry fruits.
RESUMEN
Se realizoÌ un estudio comparativo de propiedades antioxidantes, actividad de antiagregacion plaquetaria, anaÌlisis transcripcional de genes de biosiÌntesis de flavonoides y contenido de estos en Fragaria x ananassa, F. vesca and F. chiloensis subsp chiloensis f. chiloensis and f. patagonica. La mayor actividad removedora de radicales libres por DPPH se observoÌ en F. chiloensis f. chiloensis, mientras F. vesca presentoÌ la mayor capacidad antioxidante mediante FRAP. Transcritos relacionados con biosiÌntesis de flavonoides fueron mas abundantes en F. x ananassa y menores en F. vesca. Adicionalmente, todos los extractos de frutillas mostraron efectos antiagregante (1 mg mL-1), pero F. vesca and F. chiloensis subsp. chiloensis f. patagonica fueron activos a concentraciones menores. Este estudio sugiere que efectos de antiagregacioÌn plaquetaria en distintas frutillas podriÌa deberse a isoflavonas y precursores de flavonoides ademaÌs de antocianinas. Los resultados podriÌan ser uÌtiles en programas de mejoramiento geneÌtico para mejorar el contenido de compuestos saludables en frutilla.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plant Extracts
/
Fragaria
/
Antioxidants
Language:
English
Journal:
Bol. latinoam. Caribe plantas med. aromát
Journal subject:
Botany
/
Medicine
/
Plantas Medicinais
/
Terapias Complementares
Year:
2018
Type:
Article
/
Project document
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Talca/CL
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