Capsiate treatment in liver surgeries may compromise its recovery
Acta cir. bras
;
33(5): 439-445, May 2018. graf
Article
in English
| LILACS
| ID: biblio-949344
ABSTRACT
Abstract Purpose:
To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats.Methods:
The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH.Results:
Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations.Conclusion:
Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Capsaicin
/
Hepatectomy
/
Liver
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
PUC-Campinas/BR
/
Pontifícia Universidade Católica de Campinas/BR
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