Influence of addition of 2-[3-(2H-benzotriazol-2-YL)- 4-hydroxyphenyl] ethyl methacrylate to an experimental adhesive system

ABSTRACT

The aim of this study was to evaluate the addition of 2-[3-(2HBenzotriazol- 2-yl)-4-hydroxyphenyl]ethyl methacrylate (BTAM) to an experimental adhesive resin. An experimental base adhesive resin was formulated with BisGMA, TEGDMA and HEMA, to which BTAM was added at 1, 2.5 and 5%, in weight. One group with no addition was used as control. The experimental adhesives were evaluated for antibacterial potential (against Streptococcus mutans), degree of conversion with FTIR, softening in solvent and microRaman interface analyses. Data were analyzed by Kruskal-Wallis, paired t test and ANOVA and Tukey, considering a 5% level of significance. The results showed antibacterial activity of 5% BTAM against S. mutans (p<0.05), however, no difference was found among BTAM groups (p> 0.05). The results of degree of conversion and softening of solvent showed no statistical difference between BTAM and control groups (p>0.05). The addition of 5% BTAM showed higher antibacterial activity than the negative control, and copolymerization with comonomer blend of adhesive resin and BTAM was detected at the dentin/ adhesive interface.

RESUMO

O objetivo do presente estudo foi avaliar a adicao do 2-[3-(2HBenzotriazol- 2-yl)-4-hidroxifenil]etil metacrilato (BTAM) a um adesivo experimental. Uma resina adesiva base experimental foi formulada com BisGMA, TEGDMA e HEMA e a essa resina foi adicionado o BTAM nas concentracoes de 1, 2,5 e 5%, em peso, alem de um grupo controle sem adicao. Os adesivos experi - mentais foram avaliados quanto ao potencial antimicrobiano contra Streptococos mutans, grau de conversao com FTIR, degradacao em solvente e analise da interface com microespectroscopia Raman. Os dados foram analisados considerando um nivel de significancia de 5%. Os resultados obtidos no teste antimicrobiano contra S. mutans mostrou dife renca estatisticamente significativa do grupo com 5% de BTAM em relacao aos demais grupos e ao controle negativo (p<0,05). Os resultados de grau de conversao e degradacao em solvente dos grupos com BTAM nao apresentaram diferenca quando comparado ao grupo controle (p>0,05). Foi possivel observar a penetracao do BTAM na dentina. A adicao de BTAM na concentracao de 5% mostrou atividade antimicrobiana comparado ao controle negativo, alem de ter sido capaz de copolimerizar e penetrar na dentina.