Long term maintenance of glucose and lipid concentrations after Roux-en-Y gastric bypass
Arch. endocrinol. metab. (Online)
;
62(3): 346-351, May-June 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-950066
ABSTRACT
Abstract Objective:
Roux-en-Y gastric bypass (RYGB) reduces body weight and the comorbidities associated with obesity. The aim of this study was to evaluate whether glucose and lipid profiles were maintained during a 5-year follow-up period after RYGB. Subjects andmethods:
Anthropometric and laboratory data from 323 patients who had undergone this operation were analyzed. Differences in laboratory variables between the baseline and 12, 24, 36, 48 and 60 months postoperatively (PO) were assessed using a one-way ANOVA test to compare the three groups. Delta significance using one-way ANOVA was performed to assess anthropometric variable in the postoperative period (p < 0.05).Results:
77 patients (24%) were included in Group 1 (G1), 101 (32%) in Group 2 (G2), and 141 (44%) in Group 3 (G3). The majority of patients, 71.7% in G1, 82.8% in G2, and 70% in G3, showed high triglycerides (TG) before surgery. A decrease in weight loss was observed in all groups followed by an increase in body weight in G2 and G3 at 36, 48 and 60 months. Laboratory results for G1, G2 and G3 showed no significant differences between groups at baseline and during the post-operative period.Conclusion:
Our results suggest that weight regain after RYGB has no significant impact on the long-term evolution of the lipid profile and glycemia.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Obesity, Morbid
/
Glucose
/
Lipids
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arch. endocrinol. metab. (Online)
Journal subject:
Endocrinology
/
Metabolism
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Fernando Luiz Barroso/BR
/
Universidade Federal do Rio de Janeiro/BR
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