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Determination of compatibility and stability of haloperidol and morphine mixtures used in palliative care
María, Espinosa Bosch; Fuensanta, Sánchez Rojas; Catalina, Bosch Ojeda.
  • María, Espinosa Bosch; Regional Universitary Hospital of Málaga. UGC Pharmacy. ES
  • Fuensanta, Sánchez Rojas; University of Málaga. Faculty of Sciences. Department of Analytical Chemistry. ES
  • Catalina, Bosch Ojeda; University of Málaga. Faculty of Sciences. Department of Analytical Chemistry. ES
Braz. J. Pharm. Sci. (Online) ; 54(2): e17352, 2018. tab, graf
Article in English | LILACS | ID: biblio-951926
ABSTRACT
Abstract With the aim of controlling various symptoms, possible to use mixtures of different drugs within infusion devices. This should take into account the compatibility of the mixture. Factors influence the compatibility and stability of the mixtures are drug type, concentration, solvent, temperature and light. When evaluating the compatibility of the mixtures for infusion for subcutaneous via is important to consider infusion devices used and the conditions of light and temperature should simulate as far as possible the conditions in practice assistance. There are diverse studies that analyze the compatibility of drug mixtures, but there are still many possible combinations of drugs for which evidence is not available. The objective of this work is to study the compatibility and stability of several mixtures of haloperidol and morphine that can be used in solution for subcutaneous infusion.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Haloperidol / Morphine Language: English Journal: Braz. J. Pharm. Sci. (Online) Journal subject: Farmacologia / Terapˆutica / Toxicologia Year: 2018 Type: Article / Project document Affiliation country: Spain Institution/Affiliation country: Regional Universitary Hospital of Málaga/ES / University of Málaga/ES

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Full text: Available Index: LILACS (Americas) Main subject: Haloperidol / Morphine Language: English Journal: Braz. J. Pharm. Sci. (Online) Journal subject: Farmacologia / Terapˆutica / Toxicologia Year: 2018 Type: Article / Project document Affiliation country: Spain Institution/Affiliation country: Regional Universitary Hospital of Málaga/ES / University of Málaga/ES