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In situ effect of titanium tetrafluoride varnish on enamel demineralization
Alexandria, Adílis Kalina; Nassur, Camila; Nóbrega, Carolina Bezerra Cavalcanti; Valença, Ana Maria Gondim; Rosalen, Pedro Luiz; Maia, Lucianne Cople.
  • Alexandria, Adílis Kalina; Universidade Federal do Rio de Janeiro. Rio de Janeiro Dental School. Department of Pediatric Dentistry and Orthodontics. Rio de Janeiro. BR
  • Nassur, Camila; Universidade Federal do Rio de Janeiro. Rio de Janeiro Dental School. Department of Pediatric Dentistry and Orthodontics. Rio de Janeiro. BR
  • Nóbrega, Carolina Bezerra Cavalcanti; Universidade Federal de Campina Grande. Center for Rural Health and Technology. Campina Grande. BR
  • Valença, Ana Maria Gondim; Universidade Federal da Paraíba. Dental School. Department of Clinical and Social Dentistry. João Pessoa. BR
  • Rosalen, Pedro Luiz; Universidade de Campinas. Piracicaba Dental School. Department of Pharmacology, Anesthesiology, and Therapeutics. Piracicaba. BR
  • Maia, Lucianne Cople; Universidade Federal do Rio de Janeiro. Rio de Janeiro Dental School. Department of Pediatric Dentistry and Orthodontics. Rio de Janeiro. BR
Braz. oral res. (Online) ; 31: e86, 2017. tab, graf
Article in English | LILACS | ID: biblio-952118
ABSTRACT
Abstract The effect of a 4% titanium tetrafluoride (TiF 4 ) varnish on enamel demineralization was evaluated. Twelve volunteers participated in this double-blind, randomized crossover study. Six enamel specimens were positioned in intraoral appliances throughout four treatment stages 4% TiF 4 varnish (experimental varnish), 5% sodium fluoride (NaF) varnish (Duraphat ® ), placebo varnish, and negative control (deionized water). After 24 h, the varnishes were removed and plaques were allowed to accumulate. A 20% sucrose solution was dripped onto enamel blocks (10x/day). Enamel alterations were analyzed by surface microhardness (SMH), percentage of surface loss (%SML), cross-sectional microhardness (CSMH), scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDS). Student's paired t-test was used for SMH analysis and repeated-measures analysis of variance (ANOVA) for %SML and CSMH (∆Z) analyses (p-value=0.05). The TiF 4 varnish group had lower %SML than the placebo and control groups (p=0.044 and p=0.003, respectively), thus showing its capacity to inhibit surface demineralization. TiF 4 and NaF varnishes demonstrated a protective effect against mineral loss on the enamel subsurface. Both were statistically different from the control group when CSMH was analyzed (p=0.000). A titanium dioxide film was observed on enamel surfaces of the TiF 4 group SEM images. EDS confirmed the presence of titanium in all TiF 4 samples. The 4% TiF 4 varnish is a promising compound capable of reacting with enamel to protect it against surface and subsurface demineralization.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Sodium Fluoride / Titanium / Cariostatic Agents / Tooth Demineralization / Dental Enamel / Fluorides Type of study: Controlled clinical trial Limits: Adult / Humans Language: English Journal: Braz. oral res. (Online) Journal subject: Dentistry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal da Paraíba/BR / Universidade Federal de Campina Grande/BR / Universidade Federal do Rio de Janeiro/BR / Universidade de Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Sodium Fluoride / Titanium / Cariostatic Agents / Tooth Demineralization / Dental Enamel / Fluorides Type of study: Controlled clinical trial Limits: Adult / Humans Language: English Journal: Braz. oral res. (Online) Journal subject: Dentistry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal da Paraíba/BR / Universidade Federal de Campina Grande/BR / Universidade Federal do Rio de Janeiro/BR / Universidade de Campinas/BR