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Immediate laser-induced hemostasis in anticoagulated rats subjected to oral soft tissue surgery: a double-blind study
Campos, Flavio Halak de Oliveira; Ferreira, Lorraine Braga; Romano, Marcelo Munhoes; Moreira, Maria Stella; Eduardo, Carlos de Paula; Ramalho, Karen Müller.
  • Campos, Flavio Halak de Oliveira; Universidade Ibirapuera. School of Dentistry. São Paulo. BR
  • Ferreira, Lorraine Braga; Universidade de São Paulo. School of Dentistry. Department of Biomaterials. São Paulo. BR
  • Romano, Marcelo Munhoes; Universidade de São Paulo. School of Dentistry. Department of Stomatology. São Paulo. BR
  • Moreira, Maria Stella; Universidade Ibirapuera. School of Dentistry. São Paulo. BR
  • Eduardo, Carlos de Paula; Universidade de São Paulo. School of Dentistry. Department of Restorative Dentistry. São Paulo. BR
  • Ramalho, Karen Müller; Universidade Ibirapuera. School of Dentistry. São Paulo. BR
Braz. oral res. (Online) ; 32: e56, 2018. tab, graf
Article in English | LILACS | ID: biblio-952163
ABSTRACT
Abstract Given the growing trend towards medical indications for continuous use of anticoagulants, the number of patients on these medications continues to rise. The management of patients on oral anticoagulants requiring oral surgical procedures has aroused much controversy. Changes in an anticoagulation regimen are associated with an increased risk of thromboembolism. However, it seems logical and advantageous for the patients' health if surgery could be performed without any change to the anticoagulation therapy. In dentistry, high-power lasers have been poorly explored in this field. The hemostatic properties of high-power lasers could be helpful during oral soft tissue surgeries in anticoagulated patients. The aim of this study was to compare bleeding time in anticoagulated rats after lingual frenectomy performed with a scalpel or diode laser with bleeding time in healthy animals. Twenty-four male Wistar rats were assigned to four groups (n = 6) (CS) Control-Scalpel Surgery; (AS) Anticoagulated-Scalpel Surgery; (CL) Control-Laser (diode laser 810 nm/1.5 W) Surgery; and (AL) Anticoagulated-Laser Surgery (diode laser 810 nm/1.5 W). Warfarin administration was used to induce anticoagulation. Blood was blotted every 30 seconds with filter paper until bleeding stopped to verify bleeding time. Two blinded researchers performed the surgeries and collected the bleeding time data. Diode laser surgery led to complete hemostasis in rats during and after lingual frenectomy. Zero bleeding was assessed during surgeries and after diode laser surgeries in anticoagulated rats. Laser-induced hemostasis offered an alternative solution to the controversial issue of intraoperative and postoperative bleeding control in patients on anticoagulation therapy.
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Full text: Available Index: LILACS (Americas) Main subject: Blood Coagulation / Laser Coagulation / Postoperative Hemorrhage / Lasers, Semiconductor / Lingual Frenum Type of study: Etiology study / Evaluation studies / Risk factors Limits: Animals Language: English Journal: Braz. oral res. (Online) Journal subject: Dentistry Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Ibirapuera/BR / Universidade de São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Blood Coagulation / Laser Coagulation / Postoperative Hemorrhage / Lasers, Semiconductor / Lingual Frenum Type of study: Etiology study / Evaluation studies / Risk factors Limits: Animals Language: English Journal: Braz. oral res. (Online) Journal subject: Dentistry Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Ibirapuera/BR / Universidade de São Paulo/BR