Acute kidney injury following radical cystectomy and urinary diversion: predictors and associated morbidity
Int. braz. j. urol
;
44(4): 726-733, July-Aug. 2018. tab
Article
in English
| LILACS
| ID: biblio-954086
ABSTRACT
ABSTRACT Introduction:
Acute kidney injury (AKI) after major surgeries is associated with significant morbidity and mortality. We aim to report incidence, predictors and associated comorbidities of AKI after radical cystectomy in a large cohort of patients. Materials andMethods:
We conducted a retrospective analysis of 1000 patients who underwent open radical cystectomy in a tertiary referral center. Perioperative serum creatinine measurements were used to define AKI according to the RIFLE criteria (as Risk, Injury and Failure). The predictors of AKI after surgery were determined using univariate and multivariate analyses.Results:
Out of 988 evaluable patients, AKI developed in 46 (4.7%). According to RIFLE criteria; AKI-Risk, AKI-Injury and AKI-Failure occurred in 26 (2.6%), 9 (0.9%) and 11 (1.1%) patients, respectively. Multivariate analysis showed that performing nephroureterectomy with cystectomy (Odds ratio [OR] 4.3; 95% Confidence interval [CI] 1.3-13.6; p=0.01) and the development of high grade complications (OR 3.8; 95% CI 1.9-7.2; p<0.0001) were independently associated with AKI.Conclusions:
AKI is a significant morbidity after radical cystectomy and the term should be included during routine cystectomy morbidity assessment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Postoperative Complications
/
Urinary Diversion
/
Cystectomy
/
Acute Kidney Injury
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2018
Type:
Article
Affiliation country:
Egypt
Institution/Affiliation country:
Mansoura University/EG
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