Expression of Wnt and beta-catenin in mouse tooth germs and chick facial primordia: a comparison / Expresión de Wnt y beta-catenina en gérmenes de dientes de ratón y primordios faciales de polluelos: una comparación
Int. j. morphol
;
36(2): 569-575, jun. 2018. graf
Article
in English
| LILACS
| ID: biblio-954156
ABSTRACT
In order to compare Wnt/ beta-catenin expression in mouse and chick facial primordia during development, we performed an immunohistochemical analysis of both protein expressions in E12 to E17 mouse embryos and in E3 and E10 chick embryos. During odontogenesis, from bud to bell stage, both proteins exhibit similar fixation patterns, with epithelial and mesenchymal immunoreactivity, consistant with literature data. Double labelling demonstrates that the same cells express both antigens, even in undifferentiated mesenchyme. The enamel knot, and the ameloblastic and odontoblastic layers are stained at the same manner. In the chick, Wnt and beta-catenin are diffusely present on craniofacial mesenchyme. In both species, premuscular blastemata express Wnt and b-catenin, but Wnt is specifically expressed on the perichondrium and ossification centers, suggesting a role independent from beta-catenin pathway.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tooth
/
Embryo, Nonmammalian
/
Wnt Proteins
/
Beta Catenin
Limits:
Animals
Language:
English
Journal:
Int. j. morphol
Journal subject:
Anatomy
Year:
2018
Type:
Article
Affiliation country:
Belgium
Institution/Affiliation country:
Université Libre de Bruxelles/BE
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