Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case
Rev. Soc. Bras. Med. Trop
;
51(3): 393-396, Apr.-June 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-957422
ABSTRACT
Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.
Full text:
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Index:
LILACS (Americas)
Main subject:
Organometallic Compounds
/
Pentamidine
/
Amphotericin B
/
Leishmaniasis, Visceral
/
Meglumine
/
Antiprotozoal Agents
Limits:
Humans
/
Infant
/
Male
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital Infantil Varela Santiago/BR
/
Universidade Federal do Rio Grande do Norte/BR
/
Universidade Potiguar/BR
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