Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario: casos clínicos / Extracorporeal cytokine hemadsorption for the treatment of refractory septic shock: report of two cases
Rev. méd. Chile
;
146(6): 796-801, jun. 2018. tab, graf
Article
in Spanish
| LILACS
| ID: biblio-961461
ABSTRACT
If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Shock, Septic
/
Cytokines
/
Renal Dialysis
/
Hemoperfusion
Limits:
Female
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2018
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
HUAP Hospital de Urgencia Asistencia Pública/CL
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