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Brote urbano de leishmaniasis en Colombia / Urban outbreak of leishmaniasis in Colombia
Manotas-Berdugo, Hernán; Toro-Maldonado, Jessica; Rodríguez-Rodríguez, Jairo; Salgado-García, Doris.
  • Manotas-Berdugo, Hernán; Hospital Universitario Hernando Moncaleano. Neiva. CO
  • Toro-Maldonado, Jessica; Hospital Universitario Hernando Moncaleano. Neiva. CO
  • Rodríguez-Rodríguez, Jairo; Hospital Universitario Hernando Moncaleano. Neiva. CO
  • Salgado-García, Doris; Hospital Universitario Hernando Moncaleano. Neiva. CO
Rev. salud pública ; 20(1): 89-93, ene.-feb. 2018. tab
Article in Spanish | LILACS | ID: biblio-962097
RESUMEN
RESUMEN Objetivos Describir las características epidemiológicas, clínicas y el tratamiento de niños con leishmaniasis visceral en Neiva, Huila. Metodologia Se realizó un estudio descriptivo del brote de leshmaniasis visceral en niños de la zona urbana de Neiva, Huila, entre los meses de abril a junio de 2012. Resultados Se presentaron siete casos, en niños menores de cinco años, con fiebre prolongada, hepato-esplenomegalia, anemia severa y leucopenia. Cinco ingresaron con trombocitopenia severa, sin manifestaciones hemorrágicas. Seis pacientes recibieron manejo de primera línea con miltefosine, cinco presentaron fracaso terapéutico y se escalonó tratamiento a anfotericina B, de los cuales dos recibieron anfotericina liposomal y tres anfotericina deoxicolato. El principal vector identificado fue la Lutzomyia gomezi y los reservoirios indentifiacados fueron caninos. Conclusión Se describe el primer brote de leishmaniasis visceral en zona urbana, en población pediátrica sin casos de mortalidad. La mayoría de los casos con buena respuesta a Anfotericina B.(AU)
ABSTRACT
ABSTRACT Objectives To describe the epidemiology, clinical characteristics and treatment of children with visceral Leishmaniasis in Neiva- Huila, from April to June 2012. Methodology We performed a descriptive study of an outbreak of visceral leshmaniasis in children from the urban area of Neiva. Results There were seven cases in children younger than five years. All of them had prolonged fever, hepato-splenomegaly, severe anemia and leukopenia. Five were admitted with severe thrombocytopenia, without hemorrhagic manifestations. Six patients received first-line treatment with miltefosine, five of them had treatment failure requirirng therapy escalation to amphotericin B, two received liposomal amphotericin B and three deoxycholate amphotericin B. The main vector identified was the Lutzomyia gomezi and its main reservoir were canines. Conclusion We describe the first visceral leishmaniasis outbreak in children living in an urban area, with no mortality. Most of the cases had a good response to amphotericin B.(AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Amphotericin B / Disease Outbreaks / Leishmaniasis, Visceral Type of study: Prognostic study Limits: Child, preschool / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Colombia Language: Spanish Journal: Rev. salud pública Journal subject: Public Health Year: 2018 Type: Article Affiliation country: Colombia Institution/Affiliation country: Hospital Universitario Hernando Moncaleano/CO

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Full text: Available Index: LILACS (Americas) Main subject: Amphotericin B / Disease Outbreaks / Leishmaniasis, Visceral Type of study: Prognostic study Limits: Child, preschool / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Colombia Language: Spanish Journal: Rev. salud pública Journal subject: Public Health Year: 2018 Type: Article Affiliation country: Colombia Institution/Affiliation country: Hospital Universitario Hernando Moncaleano/CO