Dowling-Degos disease: a therapeutic challenge: report of a family with no response to laser treatments
Rev. chil. dermatol
; 33(4): 90-93, 2017. tab
Article
in En
| LILACS
| ID: biblio-965661
Responsible library:
CL126.2
RESUMEN
La enfermedad de Dowling-Degos (DDD), conocida también como 'anomalía reticulada y pigmentada de las flexuras' es una rara genodermatosis autosómica dominante. Se caracteriza por la aparición de máculas hiperpigmentadas de configuración reticulada; afectando principalmente los grandes pliegues como las axilas e ingles. Pudiendo, además, comprometer otros pliegues como cervicales, antecubitales, submamarios e interglúteos. Otras características asociadas son las lesiones tipo comedones y los pits palmo-plantares. Presentamos el caso de una familia con enfermedad de Dowling-Degos sin respuesta al tratamiento con laser NdYAG y CO2. Se realiza una revisión de la literatura de los tratamientos disponibles.
ABSTRACT
Dowling-Degos disease (DDD), also known as "reticulate pigmented anomaly of the flexures", is a rare autosomal dominant genodermatosis. DDD is characterized by an acquired reticular skin hyperpigmentation which begins in the axillae and groin. It later involves other body folds, including neck, inner aspects of the arms and thighs, inframammary, and intergluteal folds. Associated features include comedolike lesions on the neck or back, pitted facial or perioral scars, and epidermoid cysts. Herein we present a family (proband, mother, grandmother) with DDD that were treated with Q-switched NdYAG laser and CO2 laser without response. Treatment options are discussed and the available literature is reviewed.
Key words
Full text:
1
Index:
LILACS
Main subject:
Skin Diseases, Genetic
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Skin Diseases, Papulosquamous
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Hyperpigmentation
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Lasers, Solid-State
Limits:
Adult
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Female
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Humans
Language:
En
Journal:
Rev. chil. dermatol
Journal subject:
DERMATOLOGIA
Year:
2017
Type:
Article