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Potencial of different hydroxyapatites as biomaterials in the bone remodeling
Cassino, Pedro Carvalho; Rosseti, Larissa Schimidt; Ayala, Osmar Ignácio; Martines, Marco Antônio Utrera; Portugual, Luciane Candeloro; Oliveira, Claudio Goncalves de; Silva, Iandara Schettert; Caldas, Ruy de Araujo.
  • Cassino, Pedro Carvalho; Universidade Federal do Mato Grosso do Sul. Postgraduate Program in Health and Development. Campo Grande. BR
  • Rosseti, Larissa Schimidt; UFMS. Postgraduate Program in Health and Development. Campo Grande. BR
  • Ayala, Osmar Ignácio; UFMS. Department of Biological and Health Sciences. Campo Grande. BR
  • Martines, Marco Antônio Utrera; UFMS. Department of Biological and Health Sciences. Campo Grande. BR
  • Portugual, Luciane Candeloro; UFMS. Chemistry Institute. Campo Grande. BR
  • Oliveira, Claudio Goncalves de; UFMS. Chemistry Institute. Campo Grande. BR
  • Silva, Iandara Schettert; UFMS. Postgraduate Program in Health and Development in the Midwest Region. Campo Grande. BR
  • Caldas, Ruy de Araujo; UFMS. Postgraduate Program in Health and Development in the Midwest Region. Campo Grande. BR
Acta cir. bras ; 33(9): 816-823, Sept. 2018. tab, graf
Article in English | LILACS | ID: biblio-973498
ABSTRACT
Abstract

Purpose:

To analyze the therapeutic potentials of different hydroxyapatites used for the correction of bone defects in rats.

Methods:

Forty rats, male, albino wistar, were distributed in 4 groups. They were submitted to a 3.5 mm defect in tibia. They received low purity hydroxyapatite, Strontium hydroxyapatite and hydroxyapatite doped with gallium, having a seven day evaluation time. Histopathology slides were stained with hematoxylin-eosin, for morphological evaluation. Were analyzed inflammatory processes, necrosis, presence of osteoclasts and osteoblasts, presence of the material, presence of white cells, neovascularization and bone neoformation.

Results:

It was observed that the groups HAPSr and HAPGa, presented better results of trabecular bone, hyaline cartilage and bone marrow more organized.

Conclusion:

There was improvement in the repair of the bone defect produced, showing that these hydroxyapatites are effective osteoinductive, osteoconductive, osteintegrant agents and have biocompatibility, and may be indicated for use in defect repairs.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Tibia / Biocompatible Materials / Bone Remodeling / Bone Substitutes / Hydroxyapatites Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: UFMS/BR / Universidade Federal do Mato Grosso do Sul/BR

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Full text: Available Index: LILACS (Americas) Main subject: Tibia / Biocompatible Materials / Bone Remodeling / Bone Substitutes / Hydroxyapatites Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: UFMS/BR / Universidade Federal do Mato Grosso do Sul/BR