Potencial of different hydroxyapatites as biomaterials in the bone remodeling
Acta cir. bras
;
33(9): 816-823, Sept. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-973498
ABSTRACT
Abstract Purpose:
To analyze the therapeutic potentials of different hydroxyapatites used for the correction of bone defects in rats.Methods:
Forty rats, male, albino wistar, were distributed in 4 groups. They were submitted to a 3.5 mm defect in tibia. They received low purity hydroxyapatite, Strontium hydroxyapatite and hydroxyapatite doped with gallium, having a seven day evaluation time. Histopathology slides were stained with hematoxylin-eosin, for morphological evaluation. Were analyzed inflammatory processes, necrosis, presence of osteoclasts and osteoblasts, presence of the material, presence of white cells, neovascularization and bone neoformation.Results:
It was observed that the groups HAPSr and HAPGa, presented better results of trabecular bone, hyaline cartilage and bone marrow more organized.Conclusion:
There was improvement in the repair of the bone defect produced, showing that these hydroxyapatites are effective osteoinductive, osteoconductive, osteintegrant agents and have biocompatibility, and may be indicated for use in defect repairs.
Full text:
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Index:
LILACS (Americas)
Main subject:
Tibia
/
Biocompatible Materials
/
Bone Remodeling
/
Bone Substitutes
/
Hydroxyapatites
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UFMS/BR
/
Universidade Federal do Mato Grosso do Sul/BR
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