Your browser doesn't support javascript.
loading
Microbiology and clinical characteristics of viridans group streptococci in patients with cancer
Guerrero-Del-Cueto, Fuensanta; Ibanes-Gutiérrez, Cyntia; Velázquez-Acosta, Consuelo; Cornejo-Juárez, Patricia; Vilar-Compte, Diana.
  • Guerrero-Del-Cueto, Fuensanta; Instituto Nacional de Cancerología. Departamento de Enfermedades Infecciosas. Ciudade de México. MX
  • Ibanes-Gutiérrez, Cyntia; Instituto Nacional de Cancerología. Departamento de Enfermedades Infecciosas. Ciudade de México. MX
  • Velázquez-Acosta, Consuelo; Instituto Nacional de Cancerología. Laboratorio de Microbiología. Ciudade de México. MX
  • Cornejo-Juárez, Patricia; Instituto Nacional de Cancerología. Departamento de Enfermedades Infecciosas. Ciudade de México. MX
  • Vilar-Compte, Diana; Instituto Nacional de Cancerología. Departamento de Enfermedades Infecciosas. Ciudade de México. MX
Braz. j. infect. dis ; 22(4): 323-327, July-Aug. 2018. tab
Article in English | LILACS | ID: biblio-974230
ABSTRACT
ABSTRACT This study assessed the microbiology, clinical syndromes, and outcomes of oncologic patients with viridans group streptococci isolated from blood cultures between January 1st, 2013 and December 31st, 2016 in a referral hospital in Mexico using the Bruker MALDI Biotyper. Antimicrobial sensitivity was determined using BD Phoenix 100 according to CLSI M100 standards. Clinical information was obtained from medical records and descriptive analysis was performed.Forty-three patients were included, 22 females and 21 males, aged 42 ± 17 years. Twenty (46.5%) patients had hematological cancer and 23 (53.5%) a solid malignancy. The viridans group streptococci isolated were Streptococcus mitis, 20 (46.5%); Streptococcus anginosus, 14 (32.6%); Streptococcus sanguinis, 7 (16.3%); and Streptococcus salivarius, 2 (4.7%). The main risk factors were pyrimidine antagonist chemotherapy in 22 (51.2%) and neutropenia in 19 (44.2%) cases, respectively. Central line associated bloodstream infection was diagnosed in 18 (41.9%) cases. Septic shock occurred in 20.9% of patients, with an overall mortality of 18.6%. Only four S. mitis revealed penicillin-resistance.Our results are similar to those of other series, identifying these bacteria as emerging pathogens with significant morbidity and mortality in oncologic patients. The MALDI-TOF system increased the rate of viridans group streptococci isolation in this population.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Bacteremia / Drug Resistance, Bacterial / Catheter-Related Infections / Neoplasms Type of study: Etiology study / Practice guideline / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2018 Type: Article Affiliation country: Mexico Institution/Affiliation country: Instituto Nacional de Cancerología/MX

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Bacteremia / Drug Resistance, Bacterial / Catheter-Related Infections / Neoplasms Type of study: Etiology study / Practice guideline / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2018 Type: Article Affiliation country: Mexico Institution/Affiliation country: Instituto Nacional de Cancerología/MX