Prostaglandin A1 inhibits the replication of bovine viral diarrhea virus
Braz. j. microbiol
;
49(4): 785-789, Oct.-Dec. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-974292
ABSTRACT
ABSTRACT Bovine viral diarrhea virus can cause acute disease in livestock, leading to economic losses. We show that Prostaglandin A1 inhibits bovine viral diarrhea virus replication in Madin-Darby bovine kidney cells (94% inhibition using 5 µg/mL). Light and electron microscopy of infected cells shows that Prostaglandin A1 also prevents virus-induced vacuolization, but at higher concentrations (10 µg/mL).
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Antiviral Agents
/
Prostaglandins A
/
Bovine Virus Diarrhea-Mucosal Disease
/
Diarrhea Viruses, Bovine Viral
Limits:
Animals
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Nacional de Metrologia, Qualidade e Tecnologia/BR
/
Ministério da Agricultura, Pecuária e Abastecimento/BR
/
Universidade Federal do Rio de Janeiro/BR
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