Your browser doesn't support javascript.
loading
Prognostic significance of soft tissue deposits in laryngeal carcinoma / Importância prognóstica de depósitos de tecido mole no carcinoma laríngeo
Ozmen, Omer Afsin; Alpay, Melih; Saraydaroglu, Ozlem; Demir, Uygar Levent; Kasapoglu, Fikret; Coskun, Hamdi Hakan; Basut, Oguz Ibrahim.
  • Ozmen, Omer Afsin; Uludag University. Faculty of Medicine. Department of Otolaryngology. Bursa. TR
  • Alpay, Melih; Sanlıurfa Viransehir State Hospital. Sanlıurfa. TR
  • Saraydaroglu, Ozlem; Uludag University. Faculty of Medicine. Department of Pathology. Bursa. TR
  • Demir, Uygar Levent; Uludag University. Faculty of Medicine. Department of Otolaryngology. Bursa. TR
  • Kasapoglu, Fikret; Uludag University. Faculty of Medicine. Department of Otolaryngology. Bursa. TR
  • Coskun, Hamdi Hakan; Uludag University. Faculty of Medicine. Department of Otolaryngology. Bursa. TR
  • Basut, Oguz Ibrahim; Uludag University. Faculty of Medicine. Department of Otolaryngology. Bursa. TR
Braz. j. otorhinolaryngol. (Impr.) ; 84(5): 566-573, Sept.-Oct. 2018. tab, graf
Article in English | LILACS | ID: biblio-974348
ABSTRACT
Abstract

Introduction:

Soft tissue deposits is tumorous islands apart from lymph nodes and occasionally diagnosed in neck dissection specimens. Their importance has begun to be recognized, however, their value has not been investigated in laryngeal cancer as a single tumor site.

Objective:

To investigate the prognostic value of soft tissue deposits in patients with laryngeal carcinoma.

Methods:

Medical records of 194 patients with laryngeal carcinoma who were treated primarily by surgery and neck dissection were reviewed. Prognostic significance of soft tissue deposits was assessed along with other clinical and pathological findings. Recurrence rates, overall and disease-specific survival rates were examined.

Results:

The incidence of soft tissue deposits was found to be 7.2% in laryngeal carcinoma. N stage was more advanced in patients who had soft tissue deposits. Regional recurrence rate was higher and disease specific and overall survivals rates were significantly lower in patients with soft tissue deposits in univariate analysis. However, in multivariate analysis, soft tissue deposits were not found as an independent risk factor.

Conclusion:

In laryngeal carcinoma, soft tissue deposits was diagnosed in patients with more advanced neck disease and their significance was lesser than other factors including extranodal extension.
RESUMO
Resumo

Introdução:

Depósitos de tecido mole são ilhas tumorais diferente dos linfonodos e ocasionalmente diagnosticados em amostras de esvaziamento cervical. Sua importância começou a ser reconhecida, mas seu valor não foi investigado no câncer de laringe como um único local de tumor.

Objetivo:

Investigar o valor prognóstico do depósito de tecido mole em pacientes com carcinoma laríngeo.

Método:

Os prontuários de 194 pacientes com carcinoma laríngeo tratados principalmente por cirurgia e esvaziamento cervical foram analisados. O significado prognóstico dos depósitos de tecido mole foi avaliado juntamente com outros achados clínicos e histopatológicos. As taxas de recidiva, as taxas de sobrevida geral e específicas da doença foram avaliadas.

Resultados:

Observou-se uma incidência de depósitos de tecido mole de 7,2% no carcinoma laríngeo. O estágio N foi mais avançado em pacientes com depósitos de tecido mole. A taxa de recorrência regional foi maior e as taxas de sobrevida geral e específica da doença foram significativamente menores nesses pacientes na análise univariada. No entanto, na análise multivariada, o depósito de tecido mole não foi observado como um fator de risco independente.

Conclusão:

No carcinoma laríngeo, o depósito de tecido mole foi diagnosticado em pacientes com doença cervical mais avançada, mas sua significância foi menor do que outros fatores, inclusive a extensão extranodal.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Soft Tissue Neoplasms / Laryngeal Neoplasms Type of study: Etiology study / Prognostic study Limits: Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2018 Type: Article Affiliation country: Turkey Institution/Affiliation country: Sanlıurfa Viransehir State Hospital/TR / Uludag University/TR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Soft Tissue Neoplasms / Laryngeal Neoplasms Type of study: Etiology study / Prognostic study Limits: Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2018 Type: Article Affiliation country: Turkey Institution/Affiliation country: Sanlıurfa Viransehir State Hospital/TR / Uludag University/TR