Prognostic significance of Body Mass index in patients with localized renal cell carcinoma
Int. braz. j. urol
;
44(6): 1147-1155, Nov.-Dec. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-975654
ABSTRACT
ABSTRACT Objective:
To investigate the relationship between the pretreatment body mass index (BMI) and the clinical outcomes in patients with localized stage I - III renal cell carcinoma (RCC) surgically treated. Materials andMethods:
From January 2000 to December 2012, 798 patients with stage I - III RCC were recruited from First Affiliated Hospital and Cancer Center of Sun Yat - Sen University. Patients were divided into two groups of BMI < 25 kg / m2 or BMI ≥ 25 kg / m2 according to the World Health Organization classifications for Asian populations. The differences in the long-term survival of these two BMI groups were analyzed.Results:
The 5 - year failure - free survival rates for BMI < 25 kg / m2 and BMI ≥ 25 kg / m2 groups were 81.3% and 93.3%, respectively (P = 0.002), and the 5 - year overall survival rates were 82.5% and 93.8%, respectively (P = 0.003). BMI was a favored prognostic factor of overall survival and failure - free survival in a Cox regression model.Conclusions:
Pretreatment body mass index was an independent prognostic factor for Chinese patients surgically treated, localized stage I - III RCC.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Carcinoma, Renal Cell
/
Body Mass Index
/
Kidney Neoplasms
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2018
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Sun Yat - Sen University/CN
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