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Relationship between microcephaly and Zika virus during pregnancy: a review
Santos, Gerusinete Rodrigues Bastos dos; Aragão, Francisca Bruna Arruda; Lobão, Walder Jansen de Mello; Lima, Fabiano Rosário; Andrade, Luísa Marillac Ramos Lacerda de; Furtado, Quesia Rodrigues; Batista, José Eduardo.
  • Santos, Gerusinete Rodrigues Bastos dos; Federal University of Maranhão. São Luís. BR
  • Aragão, Francisca Bruna Arruda; Federal University of Maranhão. São Luís. BR
  • Lobão, Walder Jansen de Mello; UFMA. Pathology Department. São Luís. BR
  • Lima, Fabiano Rosário; Family Health Strategy. BR
  • Andrade, Luísa Marillac Ramos Lacerda de; Federal University of Maranhão. Family Health MS. São Luís. BR
  • Furtado, Quesia Rodrigues; s.af
  • Batista, José Eduardo; Federal University of Maranhao. Pathology Department. São Luís. BR
Rev. Assoc. Med. Bras. (1992) ; 64(7): 635-642, July 2018. tab
Article in English | LILACS | ID: biblio-976827
ABSTRACT
SUMMARY

AIM:

the present study analysed the association between Zika-virus and microcephaly during the gestational period of women in Brazil.

Methodology:

Systematic reviews of intervention research, current publications of clinical investigations were used systematic search strategies in three electronic databases PubMed, SciELO and Google academic. The following keywords were used Microcephaly, gestation, Zika-virus to perform the search, and 1020 articles were obtained after exclusion, 45 were left and 35 were eligible. The collection period was from 2004 to 2017.

Results:

Epidemiological data suggest a temporal association between the quantitative increase and the Zika-virus epidemic, especially in Northeast Brazil. It is not consensual to measure the cephalic perimeter curve to be considered.

Conclusion:

Given this, the application of techniques to accurately diagnose the relationship between causes and effects in the pathogenesis of Zika virus infection in the central nervous system should be prioritized.
RESUMO
RESUMO

OBJETIVO:

O presente estudo analisou a associação entre Zika vírus e microcefalia durante o período gestacional de mulheres no Brasil.

METODOLOGIA:

Revisões sistemáticas de pesquisas de intervenção, publicações atuais de investigações clínicas. Foram utilizadas estratégias de buscas sistemáticas em três bases de dados eletrônicos PubMed, SciELO e Google acadêmico. Utilizaram-se as palavras-chave microcefalia, gestação e Zika vírus para realizar a busca, sendo obtidos 1.020 artigos. Após a exclusão, restaram 45 e na elegibilidade, 35. O período da coleta foi de 2004 a 2017.

Resultados:

Os dados epidemiológicos preconizam uma associação temporal entre a ampliação do quantitativo e epidemia de Zika vírus, especialmente no Nordeste do Brasil. Não é consensual a mensuração da curva de perímetro cefálico a ser considerada.

CONCLUSÃO:

Visto isso, deve ser priorizada a aplicação de técnicas para diagnosticar com precisão as relações entre causas e efeitos na patogênese da infecção pelo Zika vírus no sistema nervoso central.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pregnancy Complications, Infectious / Zika Virus Infection / Microcephaly Type of study: Diagnostic study / Systematic reviews Limits: Female / Humans / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Family Health Strategy/BR / Federal University of Maranhao/BR / Federal University of Maranhão/BR / UFMA/BR

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Full text: Available Index: LILACS (Americas) Main subject: Pregnancy Complications, Infectious / Zika Virus Infection / Microcephaly Type of study: Diagnostic study / Systematic reviews Limits: Female / Humans / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Family Health Strategy/BR / Federal University of Maranhao/BR / Federal University of Maranhão/BR / UFMA/BR