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Multiple factors affect the regeneration of liver
Ouyang, Gaoxiong; Liu, Jianyong; Wang, Peng; Ren, Yuan; Yi, Ping; Zhou, Quan; Chen, Jun; Xiang, Bangde; Zhang, Yumei; Zhang, Zhiming; Li, Lequn.
  • Ouyang, Gaoxiong; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Liu, Jianyong; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Wang, Peng; Guangxi Medical University. Affiliated Cancer Hospital. Department of Radiology. Nanning. CN
  • Ren, Yuan; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Yi, Ping; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Zhou, Quan; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Chen, Jun; Guangxi Medical University. Affiliated Cancer Hospital. Department of Pathology. Nanning. CN
  • Xiang, Bangde; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Zhang, Yumei; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Zhang, Zhiming; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
  • Li, Lequn; Guangxi Medical University. Affiliated Cancer Hospital. Department of Hepatobiliary Surgery. Nanning. CN
Rev. Assoc. Med. Bras. (1992) ; 64(9): 791-798, Sept. 2018. graf
Article in English | LILACS | ID: biblio-976857
ABSTRACT
SUMMARY OBJECTIVE To study factors affecting the liver regeneration after hepatectomy METHODS With 3D reconstitution technology, liver regeneration ability of 117 patients was analysed, and relative factors were studied. RESULTS There was no statistically difference between the volume of simulated liver resection and the actual liver resection. All livers had different degrees of regeneration after surgery. Age, gender and blood indicators had no impact on liver regeneration, while surgery time, intraoperative blood loss, blood flow blocking time and different ways of liver resection had a significant impact on liver regeneration; In addition, the patients' own pathological status, including, hepatitis and liver fibrosis all had a significant impact on liver regeneration. CONCLUSION 3D reconstitution model is a good model to calculate liver volume. Age, gender, blood indicators and biochemistry indicators have no impact on liver regeneration, but surgery indicators and patients' own pathological status have influence on liver regeneration.
RESUMO
RESUMO OBJETIVO Estudar os fatores que afetam a regeneração hepática após hepatectomia. MÉTODOS A capacidade de regeneração hepática de 117 pacientes foi analisada com a tecnologia de reconstituição 3D e foram estudados os fatores relacionados. RESULTADOS Não houve diferença estatística significante entre o volume de ressecção hepática simulada e a ressecção atual. Todos os fígados apresentaram diferentes graus de regeneração após cirurgia. Idade, gênero e indicadores sanguíneos não tiveram impacto na regeneração hepática, enquanto que tempo de cirurgia, perda sanguínea intraoperatória, tempo de bloqueio do fluxo sanguíneo e diferentes formas de ressecção mostraram impacto significante na regeneração do órgão. Além disso, condições patológicas dos pacientes, incluindo hepatite e fibrose hepática, tiveram impacto significante na regeneração hepática. CONCLUSÃO O modelo de reconstituição 3D é um bom modelo para calcular o volume do fígado. Idade, gênero, indicadores sanguíneos e bioquímicos não tiveram impacto na regeneração hepática, mas indicadores operatórios e condição patológica dos pacientes mostraram influência na regeneração do órgão.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Hepatocellular / Hepatectomy / Liver Neoplasms / Liver Regeneration Type of study: Etiology study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: Guangxi Medical University/CN

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Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Hepatocellular / Hepatectomy / Liver Neoplasms / Liver Regeneration Type of study: Etiology study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: Guangxi Medical University/CN