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The relationship between neutrophil to lymphocyte ratio and postoperative pain in total knee and hip arthroplasty / Relação entre a proporção neutrófilo/linfócito e a dor pós-operatória em artroplastia total de joelho e quadril
Canbolat, Nur; Buget, Mehmet Ilke; Sivrikoz, Nukhet; Altun, Demet; Kucukay, Suleyman.
  • Canbolat, Nur; Istanbul University. Istanbul Medical Faculty. Department of Anesthesiology. Istanbul. TR
  • Buget, Mehmet Ilke; Istanbul University. Istanbul Medical Faculty. Department of Anesthesiology. Istanbul. TR
  • Sivrikoz, Nukhet; Istanbul University. Istanbul Medical Faculty. Department of Anesthesiology. Istanbul. TR
  • Altun, Demet; Istanbul University. Istanbul Medical Faculty. Department of Anesthesiology. Istanbul. TR
  • Kucukay, Suleyman; Istanbul University. Istanbul Medical Faculty. Department of Anesthesiology. Istanbul. TR
Rev. bras. anestesiol ; 69(1): 42-47, Jan.-Feb. 2019. tab, graf
Article in English | LILACS | ID: biblio-977425
ABSTRACT
Abstract Background and

objectives:

Neutrophil to lymphocyte ratio is a simple, cost-effective and easily applicable inflammation indicator that is being used frequently in mortality, morbidity and prognosis studies in the recent years. We evaluated the relationship between neutrophil to lymphocyte ratio and postoperative pain in patients undergoing total hip arthroplasty and total knee arthroplasty. Material and

methods:

We included 101 patients who preferred spinal anesthesia and intravenous patient-controlled analgesia in accordance and divided them into two groups, total hip arthroplasty and total knee arthroplasty. We recorded demographic information, duration of operation, length of hospital stay, analgesics consumption, neutrophil to lymphocyte ratio results and postoperative pain using Visual Analog Scale.

Results:

The morphine consumption of the patients was as follows in group total hip arthroplasty and total knee arthroplasty at the 4th hour 7.38 mg, 7.80 mg; 8th hour 12.19 mg, 13.29 mg; 12th hour 16.94 mg, 19.18 mg; 24th hour 25.97 mg, 27.98 mg; 48th hour 36.38 mg, 39.59 mg. The Visual Analog Scale scores of the patients was as follows in group total hip arthroplasty and total knee arthroplasty at the 4th hour 4.10, 4.51; 8th hour 3.02, 3.43; 12th hour 2.29, 2.55; 24th hour 1.90, 1.87; 48th hour 1.08, 1.13. In group total hip arthroplasty, we found a statistically significant association between postoperative neutrophil to lymphocyte ratio and the Visual Analog Scale values on the 48th hour in a positive direction (r = 0.311; P = 0.031; P < 0.05).

Conclusion:

Neutrophil to lymphocyte ratio can be accepted as a relatively objective method for the diagnosis of postoperative pain.
RESUMO
Resumo Justificativa e

objetivos:

A proporção entre neutrófilo/linfócito é um indicador de inflamação simples, custo-efetivo e de fácil aplicação que vem sendo usado com frequência em estudos de mortalidade, morbidade e prognóstico nos últimos anos. Avaliamos a relação entre a proporção neutrófilo/linfócito e a dor pós-operatória em pacientes submetidos à artroplastia total de quadril e artroplastia total de joelho. Material e

métodos:

No total, 101 pacientes que preferiram a raquianestesia e a analgesia venosa controlada pelo paciente foram incluídos e divididos em dois grupos neste estudo artroplastia total de quadril e artroplastia total de joelho. Os dados demográficos e os tempos de operação, internação hospitalar e consumo de analgésicos e os resultados da proporção neutrófilo/linfócito e da dor pós-operatória foram registrados usando uma escala visual analógica.

Resultados:

O consumo de morfina dos pacientes submetidos à artroplastia total de quadril e artroplastia total de joelho nas horas 4, 8, 12, 24 e 45 foi de, respectivamente 7,38 mg e 7,80 mg; 12,19 mg e 13,29 mg; 16,94 mg e 19,18 mg; 25,97 mg e 27,98 mg; 36,38 mg e 39,59 mg. Os escores obtidos na escala visual analógica dos pacientes submetidos à artroplastia total de quadril e artroplastia total de joelho nas horas 4, 8, 12, 24 e 48 foram, respectivamente 4,10 e 4,51; 3,02 e 3,43; 2,29 e 2,55; 1,90 e 1,87; 1,08 e 1,13. Na artroplastia total do quadril, uma associação estatisticamente significativa foi encontrada entre a proporção neutrófilo/linfócito no pós-operatório e os valores da escala visual analógica na 48ª hora em uma direção positiva (r = 0,311; p = 0,031; p < 0,05).

Conclusão:

A proporção neutrófilo/linfócito pode ser aceita como um método relativamente objetivo para o diagnóstico da dor pós-operatória.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pain, Postoperative / Lymphocytes / Arthroplasty, Replacement, Hip / Arthroplasty, Replacement, Knee / Neutrophils Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. bras. anestesiol Journal subject: Anesthesiology Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Istanbul University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Pain, Postoperative / Lymphocytes / Arthroplasty, Replacement, Hip / Arthroplasty, Replacement, Knee / Neutrophils Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. bras. anestesiol Journal subject: Anesthesiology Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Istanbul University/TR