Act values after neutralization lower than pre-heparinization act leads to lower operative times, bleeding, and post-operative transfusions in cabg pa
Rev. bras. cir. cardiovasc
;
33(6): 588-596, Nov.-Dec. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-977474
ABSTRACT
Abstract Objective:
To evaluate if lower activated coagulation time (ACT) value after neutralization than preoperative ACT value was effective in reducing bleeding, operative times, and post-operative transfusions in patients underwent coronary artery bypass grafting (CABG).Methods:
Retrospective selection of 398 patients from January 2014 to May 2017. Patients were divided into 2 groups according to final ACT after neutralization A - final ACT lower than preoperative ACT; and B - final ACT higher than or equal to preoperative ACT. Hemostatic time, intraoperative blood loss, ACT after final neutralization, mediastinal blood loss, and transfusion requirements were observed.Results:
The hourly blood loss in the Group A was generally lower than in the Group B at first 3 hours, which has significant difference (P<0.05). However, there was no difference after 3 hours between the two groups. Operative time, intraoperative blood loss, mediastinal blood loss, transfusion requirements, and drainage in the first postoperative 12 hours in the Group A were lower than in Group B, which has significant difference (P<0.05).Conclusion:
As a result, final ACT values lower than pre-heparinization ACT values are safe and lead to lower operative times, bleeding, and post-operative transfusions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Heparin
/
Coronary Artery Bypass
/
Blood Loss, Surgical
/
Postoperative Hemorrhage
Type of study:
Observational study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. bras. cir. cardiovasc
Journal subject:
Cardiology
/
General Surgery
Year:
2018
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
1st Central Hospital of Tianjin/CN
/
Jilin University/CN
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