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Assessment of non-invasive tear break-up time and tear meniscus height after instillation of three different formulations of anesthetic eye drops by Oculus Keratograph 5M / Avaliação do tempo de ruptura lacrimal não invasivo e da altura do menisco lacrimal após a instilação de três diferentes formulações de colírio anestésico por Oculus Keratograph 5M
Safarzadeh, Masoud; Safavi, Mahmoud; Azizzadeh, Parvin; Akbarshahi, Pedram.
  • Safarzadeh, Masoud; Iran University of Medical Sciences. Faculty of Rehabilitation Sciences. Department of Optometry. Tehran. IR
  • Safavi, Mahmoud; Iran University of Medical Sciences. School of Rehabilitation Sciences. Department of Optometry. Tehran. IR
  • Azizzadeh, Parvin; Tehran University of Medical Sciences. Faculty of Medicine. Department of Ophthalmology. Tehran. IR
  • Akbarshahi, Pedram; Shahid Beheshti of Medical Sciences. Department of Optometry. Tehran. IR
Rev. bras. oftalmol ; 77(5): 244-247, set.-out. 2018. tab
Article in English | LILACS | ID: biblio-977870
ABSTRACT
Abstract

Purpose:

To assess the non-invasive tear break-up time (NITBUT) and tear meniscus height (TMH) after instilling the three different types of anesthetic eye drops by Oculus Keratograph 5M.

Methods:

In this prospective study, 85 healthy subjects (85 eyes) were randomly divided into three groups. The groups were randomly received lidocaine hydrochloride 2%, proparacaine hydrochloride 0.5%, and tetracaine hydrochloride 0.5%. The qualitative and quantitative parameters of tear film were assessed using NITBUT and TMH, respectively. In all groups, the quantity of tear film using TMH was measured in the right eye of subjects, while the quality of tear film using NITBUT was assessed in the left eye. The analysis of variance (ANOVA) was used to compare the difference between before and after the intervention. A P-value < 0.05 was considered significant.

Results:

Differences for TMH and NITBUT between before and after applying lidocaine hydrochloride 2% were not statistically significant (P > 0.05). The mean values of NITBUT and TMH after the instillation of proparacaine hydrochloride 0.5% showed a significant decrease than before the intervention (P < 0.05). Also, after the use of tetracaine hydrochloride 0.5%, the mean value of NITBUT was significantly increased (P < 0.05), but the mean value of TMH was significantly decreased than before the intervention (P < 0.05).

Conclusion:

Our study showed that lidocaine hydrochloride 2% as an anesthetic eye drops can be an appropriate choice for eye examinations due to a lack of significant effect on the quantity and quality of tear film.
RESUMO
Resumo

Objetivo:

Avaliar o tempo de ruptura lacrimal não invasivo (NITBUT) e a altura do menisco lacrimal (TMH) após instilar os três tipos diferentes de colírio anestésico pelo Oculus Keratograph 5M.

Métodos:

Neste estudo prospectivo, 85 indivíduos saudáveis (85 olhos) foram divididos aleatoriamente em três grupos. Os grupos receberam aleatoriamente cloridrato de lidocaína a 2%, cloridrato de proparacaína a 0.5% e cloridrato de tetracaína a 0.5%. Os parâmetros qualitativos e quantitativos do filme lacrimal foram avaliados utilizando NITBUT e TMH, respectivamente. Em todos os grupos, a quantidade de filme lacrimal utilizando TMH foi medida no olho direito dos sujeitos, enquanto a qualidade do filme lacrimal usando NITBUT foi avaliada no olho esquerdo. A análise de variância (ANOVA) foi utilizada para comparar a diferença entre antes e depois da intervenção. Um valor de P < 0.05 foi considerado significativo.

Resultados:

Diferenças para TMH e NITBUT entre antes e depois da aplicação de cloridrato de lidocaína a 2% não foram estatisticamente significantes (P > 0.05). Os valores médios de NITBUT e TMH após a instilação de cloridrato de proparacaína a 0.5% mostraram uma diminuição significativa do que antes da intervenção (P < 0.05). Além disso, após o uso de cloridrato de tetracaína a 0.5%, o valor médio de NITBUT foi significativamente aumentado (P < 0.05), mas o valor médio de TMH foi significativamente menor do que antes da intervenção (P < 0.05).

Conclusão:

Nosso estudo mostrou que o cloridrato de lidocaína a 2% como colírio anestésico pode ser uma escolha apropriada para exames oftalmológicos devido à falta de efeito significativo sobre a quantidade e a qualidade do filme lacrimal.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Ophthalmic Solutions / Propoxycaine / Tears / Tetracaine / Corneal Topography / Anesthetics, Local / Lidocaine Type of study: Controlled clinical trial / Observational study / Qualitative research Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2018 Type: Article Affiliation country: Iran Institution/Affiliation country: Iran University of Medical Sciences/IR / Shahid Beheshti of Medical Sciences/IR / Tehran University of Medical Sciences/IR

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Full text: Available Index: LILACS (Americas) Main subject: Ophthalmic Solutions / Propoxycaine / Tears / Tetracaine / Corneal Topography / Anesthetics, Local / Lidocaine Type of study: Controlled clinical trial / Observational study / Qualitative research Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2018 Type: Article Affiliation country: Iran Institution/Affiliation country: Iran University of Medical Sciences/IR / Shahid Beheshti of Medical Sciences/IR / Tehran University of Medical Sciences/IR