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Caracterização molecular e perfil de suscetibilidade de Cryptococcus e outras leveduras melanizadas de ambiente contaminado com fungicidas azólicos
São Paulo, SP; s.n; 2016. 126 p. ilus, tab, graf.
Thesis in Portuguese | LILACS, SES-SP, SESSP-CTDPROD, SES-SP, SESSP-ACVSES, SESSP-TESESESSP, SES-SP | ID: biblio-983534
RESUMO
Cepas fúngicas ambientais estão sujeitas, continuamente, à grande diversidade de ações antrópicas, como a exposição a f u n g i c i d a, o que poderia induzir à resistência adquirida a fármacos antifúngicos com estrutura química e mecanismo de ação semelhante. A resistência adquirida a fármacos azólicos(fluconazol, itraconazol, v o r i c o n a z o l, etc.) tem importante implicação clínica.O objetivo deste estudo foi isolar e caracterizar leveduras melanizadas de origem ambiental, do gênero Cryptococcus e do grupo Black Yeast Fungi (BYF),e determinar seu perfil de sensibilidade a fármacos e fungicidas azólicos...
ABSTRACT
Environmental fungal strains are subject continuously to the wide range of humanactivities, such as exposure to fungicide, which could lead to acquired resistance to antifungal drugs with similar chemical structure and mechanism of action. Theacquired resistance to azole drugs (fluconazole, itraconazole, voriconazole, etc.)has important clinical implications. The aim of this study was to isolate and characterize melanized yeast environmental origin, gender Cryptococcus and Black Yeast Fungi group (BYF), and determine its susceptibility profile to drugs and azole fungicides...
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Yeasts / Cryptococcus / Disease Susceptibility / Environmental Pollution / Disease Resistance / Antifungal Agents Language: Portuguese Year: 2016 Type: Thesis

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Full text: Available Index: LILACS (Americas) Main subject: Yeasts / Cryptococcus / Disease Susceptibility / Environmental Pollution / Disease Resistance / Antifungal Agents Language: Portuguese Year: 2016 Type: Thesis