Fatal Disseminated Herpes Simplex in a very premature neonate
Autops. Case Rep
;
8(4): e2018050, Oct.-Dec. 2018. ilus
Article
in English
| LILACS
| ID: biblio-986542
ABSTRACT
Herpes Simplex Virus infections (HSV) are ubiquitous. The neonatal HSV infection (NHSV) is rare. The incidence is estimated globally at only 10.3 per 100,000 births, but it can cause devastating disease in premature infants. Both HSV-1 and HSV-2 can be the etiologic agents in this type of vertically transmittted NHSV infection. Here we describe the pathological findings from a complete autopsy of a very low birth weight infant who succumbed to the infection despite early institution of antiviral treatment. We urge more awareness of this disease with continued surveillance; every effort should be taken to make an early diagnosis and thus prevent this devastating disease.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pregnancy Complications, Infectious
/
Herpes Simplex
Type of study:
Screening study
Limits:
Female
/
Humans
/
Infant, Newborn
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2018
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
University of Arizona/US
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