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Calprotectina fecal: utilidad en el diagnóstico diferencial de enfermedad inflamatoria intestinal y síndrome intestino irritable en adultos / Fecal Calprotectin: utility in the differential diagnosis of inflammatory bowel disease and irritable bowel syndrome in adults
Covarrubias R, Natalia; Madrid S, Ana María; Rojas B, René; Gompertz G, Macarena.
  • Covarrubias R, Natalia; Hospital Clínico Universidad de Chile. Departamento de Medicina. Sección de Gastroenerología Laboratorio de Gastroenterología. Santiago. CL
  • Madrid S, Ana María; Hospital Clínico Universidad de Chile. Departamento de Medicina. Sección de Gastroenterología. Santiago. CL
  • Rojas B, René; Hospital Clínico Universidad de Chile. Departameno de Medicina. Sección de Gastroenterología. Santiago. CL
  • Gompertz G, Macarena; Hospital Clínico Universidad de Chile. Departamento de Medicina. Sección de Gastroenterología. Santiago. CL
Rev. Hosp. Clin. Univ. Chile ; 29(2): 166-172, 2018. graf
Article in Spanish | LILACS | ID: biblio-986840
ABSTRACT
Differentiation between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) can be complex as their symptoms are often similar and unspecific. Fecal biomarkers could be useful to select patients with suspected organic diseases for colonoscopy, with the aim to improve early diagnosis and to avoid unnecessary invasive studies. Fecal calprotectin (FC) is a protein found mainly in neutrophils that is released into the feces as a result of cell disruption and apoptosis. Currently, FC is a simple and non-invasive biomarker of intestinal inflammation. Inflammatory gastrointestinal disorders are associated with high levels of FC, as occurs in IBD. This review focuses on FC as a useful tool for differential diagnosis between IBS and IBD in adults. (AU)
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Inflammatory Bowel Diseases / Leukocyte L1 Antigen Complex / Irritable Bowel Syndrome Type of study: Diagnostic study / Screening study Limits: Adult / Female / Humans / Male Language: Spanish Journal: Rev. Hosp. Clin. Univ. Chile Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Clínico Universidad de Chile/CL

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Full text: Available Index: LILACS (Americas) Main subject: Inflammatory Bowel Diseases / Leukocyte L1 Antigen Complex / Irritable Bowel Syndrome Type of study: Diagnostic study / Screening study Limits: Adult / Female / Humans / Male Language: Spanish Journal: Rev. Hosp. Clin. Univ. Chile Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Clínico Universidad de Chile/CL