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Evaluation of nutritional status in children with amblyopia / Avaliação do estado nutricional de crianças com ambliopia
Subasi, Sevgi; Altintas, Ozgul; Mercan, Selda; Cizmecioglu, Filiz; Toprak, Muge; Emre, Esra.
  • Subasi, Sevgi; Körfez State Hospital. Department of Ophthalmology. Kocaeli. TR
  • Altintas, Ozgul; Acıbadem University Medical Faculty. Department of Ophthalmology. Istanbul. TR
  • Mercan, Selda; Istanbul University. Institute of Forensic Sciences. Forensic Toxicology Laboratory. Istanbul. TR
  • Cizmecioglu, Filiz; Kocaeli University. Department of Pediatrics. Division of Pediatric Endocrinology and Diabetes. Kocaeli. TR
  • Toprak, Muge; Gebze Fatih State Hospital. Department of Ophthalmology. Kocaeli. TR
  • Emre, Esra; Çerkezköy State Hospital. Department of Ophthalmology. Tekirdağ. TR
Arq. bras. oftalmol ; 82(2): 141-148, Mar.-Apr. 2019. tab
Article in English | LILACS | ID: biblio-989402
ABSTRACT
ABSTRACT

Purpose:

We aimed to compare the body mass index and vitamin and mineral status of children with and without amblyopia.

Methods:

Amblyopic children aged between 5 and 18 years (n=46) and age-matched control children (n=32) were evaluated in terms of anthropometric parameters, including height, weight, body mass index and demographic features. Serum vitamin B12 and folate were measured using an Advia Centaur XP (Siemens, Ireland) biochemistry analyzer. We evaluated the inorganic mineral elements from hair samples with inductively coupled plasma-mass spectrometry using a Thermo XSeries 2 analyzer (Thermo Fisher Scientific, Bremen, Germany).

Results:

No significant difference was found between the two groups in terms of height, weight, and body mass index or serum B12 and folate concentrations (p>0.05). Children with severe amblyopia had lower vitamin B12 and folate and higher body mass index. The levels of phosphorus (p=0.012), selenium (p=0.002), molybdenum (p<0.001), iodine (p=0.002), chromium (p=0.022), boron (p<0.001), and beryllium (p=0.005) were all significantly lower in the amblyopia group compared to the control group. All of these minerals, except phosphorus, were also significantly lower in those with severe amblyopia compared to those with milder amblyopia and controls (p<0.05).

Conclusion:

Amblyopic children are significantly deficient in some inorganic elements. Inorganic elements, vitamin B12, and folate may play an important role in the visual development of amblyopic children.
RESUMO
RESUMO

Objetivo:

Nosso objetivo foi comparar o índice de massa corporal e o nível de vitaminas e minerais de crianças com e sem ambliopia.

Métodos:

Crianças amblióticas com idades entre 5 e 18 anos (n=46) e crianças controle pareadas por idade (n=32) foram avaliadas quanto a parâmetros antropométricos, incluindo altura, peso, índice de massa corporal e características demográficas. A vitamina B12 e o folato séricos foram medidos utilizando um analisador bioquímico Advia Centaur XP (Siemens, Irlanda). Avaliamos os elementos minerais inorgânicos de amostras de cabelo com espectrometria de massa de plasma indutivamente acoplado usando um analisador Thermo XSeries 2 (Thermo Fisher Scientific, Bremen, Alemanha).

Resultados:

Não houve diferença significativa entre os dois grupos em relação à altura, peso e índice de massa corporal ou concentrações séricas de B12 e folato (p>0,05). Crianças com ambliopia severa tinham menor vitamina B12 e folato e maior índice de massa corporal. Os níveis de fósforo (p=0,012), selênio (p=0,002), molibdênio (p<0,001), iodo (p=0,002), cromo (p=0,022), boro (p<0,001) e berílio (p=0,005) foram todos significativamente menores no grupo com ambliopia em comparação com o grupo controle. Todos esses minerais, exceto o fósforo, também foram significativamente menores naqueles com ambliopia em comparação com aqueles com ambliopia leve e grupo controle (p<0,05).

Conclusão:

As crianças amblíopes são significativamente deficientes em alguns elementos inorgânicos. Elementos inorgânicos, vitamina B12 e folato podem desempenhar um papel importante no desenvolvimento visual de crianças com ambliopia.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Vitamin B 12 / Amblyopia / Nutritional Status / Folic Acid / Hair Type of study: Observational study Limits: Child / Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Ac&#305;badem University Medical Faculty/TR / Gebze Fatih State Hospital/TR / Istanbul University/TR / Kocaeli University/TR / Körfez State Hospital/TR / Çerkezköy State Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Vitamin B 12 / Amblyopia / Nutritional Status / Folic Acid / Hair Type of study: Observational study Limits: Child / Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Ac&#305;badem University Medical Faculty/TR / Gebze Fatih State Hospital/TR / Istanbul University/TR / Kocaeli University/TR / Körfez State Hospital/TR / Çerkezköy State Hospital/TR