Evaluation of incidence and histolopathological findings of soft tissue sarcomas in genitourinary tract: Uludag university experience
Int. braz. j. urol
;
45(1): 68-73, Jan.-Feb. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-989958
ABSTRACT
ABSTRACT Purpose:
In this study we aimed to review urological soft tissue sarcomas of genitourinary tract that were diagnosed in our institution and their prognostic factors for survival. Materials andMethods:
The clinical and pathological records of 31 patients who had diagnosis of soft tissue sarcomas primarily originating from the genitourinary tract between 2005-2011 were reviewed.Results:
The most common site was kidney (17 cases, 54.8%), and most common diagnosis was leiomyosarcoma (11 cases, 35.4%). A total of 24 patients (77.4%) had surgical excision. The surgical margins were positive in 7 patients who presented with local recurrence after primary resection. Twelve patients developed metastatic disease. During follow-up (range 9-70 month), 26 of the 31 patients (88.9%) were alive. Significant survival differences were found according to histological type (p 0.001), with lower survival rates for malignant fibrous histiocytoma. The tumor size, the presence of metastasis at the time of diagnosis and tumor localization were not statistically significant for overall survival.Conclusions:
In our series, prostate sarcomas, paratesticular rhabdomyosarcoma and malignant fibrous histiocytoma had poor prognosis, especially in patients presenting with metastatic disease.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Prostatic Neoplasms
/
Sarcoma
/
Testicular Neoplasms
/
Urinary Bladder Neoplasms
/
Kidney Neoplasms
Type of study:
Diagnostic study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Aged80
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2019
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Uludag University/TR
Similar
MEDLINE
...
LILACS
LIS