First case report of cryptococcosis due to Cryptococcus decagattii in a pediatric patient in Argentina
Rev. Soc. Bras. Med. Trop
;
52: e20180419, 2019. graf
Article
in English
| LILACS
| ID: biblio-990432
ABSTRACT
Abstract We report the first case of cryptococcosis due to Cryptococcus decagattii in an immunocompetent pediatric patient from an indigenous community in Argentina with a successful outcome. Two isolates (blood, cerebrospinal fluid) were genotyped by restriction fragment length polymorphism of the orotidine monophosphate pyrophosphorylase (URA5) gene as VGIV and identified by multi-locus sequence typing as C. decagattii. Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification indicated genotype VGIII. The minimum inhibitory concentration of amphotericin B, fluconazole, itraconazole, and voriconazole was determined (cerebrospinal fluid 0.25, 16, 0.12, and 0.12, blood 0.25, 4, 0.12, and 0.06, respectively, all in mg/L).
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cryptococcosis
/
Cryptococcus
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Child
/
Female
/
Humans
Country/Region as subject:
South America
/
Argentina
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2019
Type:
Article
Affiliation country:
Argentina
Institution/Affiliation country:
ANLIS (Administración Nacional de Laboratorios e Institutos de Salud)/AR
/
Hospital Público Materno Infantil/AR
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