Challenging management of hepatitis B infection in ankylosing spondylitis patients in an endemic area during immunosuppressive therapy
Rev. Soc. Bras. Med. Trop
;
52: e20180386, 2019. graf
Article
in English
| LILACS
| ID: biblio-990436
ABSTRACT
Abstract Hepatitis B infection is a global health issue. When considering patients with rheumatic diseases, this is no different. By using immunosuppressant drugs, such as DMARDs and biologics, viral reactivation is possible, leading to serious consequences on the patient. We report 3 cases of association between ankylosing spondylitis and hepatitis B with the use of immunosuppressant drugs. Case 1 was a patient with previous HBV infection using DMARD. Cases 2 and 3 were patients chronically infected by HBV during immunosuppressant therapy. The management of HBV infection during immunosuppressant therapy is challenging and needs multidisciplinary support.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Spondylitis, Ankylosing
/
Virus Activation
/
Antirheumatic Agents
/
Hepatitis B
/
Immunosuppressive Agents
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital Universitário Getúlio Vargas/BR
/
Universidade Federal do Amazonas/BR
/
Universidade Nilton Lins/BR
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